Degenerative Disc Disease Flashcards

1
Q

Explain degenerative disc disease

A

Natural deterioriation of the intervertebral disc structure.

It becomes progressively weaker and start to collapse.

Patients may remain asymptomatic or can be in a lot of pain.

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2
Q

What is degenerative disc disease related to?

A

Aging causing:

Progressive dehydration of nucleus pulposus

Daily activities lead to tears of annulus fibrosis

Injuries and pathlogy lead to instability

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3
Q

Pathophysiology

A

Three stages:

Dysfunction -> outer annular tears and separation of endplate, cartilage destruction and facet synovial reaction.

Instability -> Disc resorption and loss of disc space height
Facet capsular laxity causing subluxation and spondylolisthesis.

Restabilisation -> Osteophyte formation and canal stenosis

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4
Q

Early Clinical features

A

Localised symptoms of local spinal tenderness, contracted paraspinal muscles and hypomobility.
Painful extension of back and neck

Examination is often unremarkable.

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5
Q

Late clinical features

A

Pain becomes more severe and cause radicular leg pain or paraesthesia

+ve Lasegue sign

Worsening muscle tenderness, stiffness, reduced movement and scoliosis

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6
Q

What is Lasegue test?

A

Straight leg raise to assess for disc herniation in patients presenting with lumbago (pain in lower back).

Patient is lying down and examiner lifts the patient’s leg while knee is straight.

You can also dorsiflex the ankle +/- flex cervical spine for further assessment.

+ve = Pain is elicited during leg raising +/- ankle dorsiflexion or cervical spine flexion.

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7
Q

Dx

A

CES

Infection

Malignancy

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8
Q

Red flag assessment

A

Faecal incontinence

Urinary retention and overflow incontinence

Saddle anaesthesia

Bilateral sciatica

Immunosuppression

Chronic steroid use

Osteoporosis

IVDU

Unexplained fever

Significant trauma

Metabolic bone disease

New onset after 50 yo or hx of malignancy

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9
Q

When should imaging be done?

A

Red flags

Radiculopathy with pain for more than 6 weeks

Suspicion of spinal cord compression

If imaging would significantly alter management

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10
Q

When is spine x-ray done?

A

Hx of recent significant trauma

Known osteoporotic

Aged over 70

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11
Q

Gold standard investigation

A

MRI (majority do not require imaging however)

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12
Q

MRI findings

A

Signs of degeneration

Reduction of disc heigh

Annular tears

Endplate changes

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13
Q

Mainstay management

A

Pain relief going simple analgesics -> neuropathic pain medication

Encourage mobility + physiotherapy

Only emergency intervention if CES with laminectomy or discectomy

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14
Q

When should you refer?

A

Pain continues beyond 3 months despite analgesia.

This should be referred to pain clinic.

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15
Q

Indications of surgical intervention.

A

Spinal fusion has previous been suggested but no evidence to support surgical intervention

Surgery might make back pain worse in long term.

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