Definitions Flashcards
What is virchows triad
Venous stasis
Vascular endothelial wall injury
Hypercoagulability
Reversible respecters for DVT and PE
Trauma surgery, Aster, dinner replacement, chemotherapy mobility fractures, CVCs, obesity, air travel
Inherited disorders for Risk factors for DVT and PE
Activated proteins c resistance, antithrombin, three deficiency, proteins, C, deficiency, protein, S, deficiency, factor v, prothrombin, gene mutation
Acquired risk factors for DVT and PE
Age over 40, malignancy, previous DVT, heart failure, stroke, inflammatory, bowel disease, nephrotic syndrome, spinal cord injury, ErickA’s been superficial veins, and Boces lupus
What are risk factors for recurrent VTE
Proximal DVT and PE, malignancy mail, antiphospholipid antibody syndrome, persistent positive d-dimer residual thrombosis
Diagnostic criteria for VTE
Erythema pain, swelling, venous, distention warmth in the affected leg D dimer greater than 500 MRI
Definition of afib
Cardiac arrhythmia, characterized by loss of coordination of electrical mechanical activity in the atria
Thrombi conform in the left atrial appendage due to impaired ventricular filling in complete emptying of the atria
Major complications of a fit include stroke, heart failure, dementia, death
Symptoms of a fib
Palpitations, justice, comfort, shortness of breath, weakness, hypotension, dizziness, syncope
Management of a fIn
Preventing TIA stroke with anticoagulant drugs
Maintaining and restoring sinus rhythm
Controlling the ventricular rate
SALTE for afib
Stabilize(monitor heart rate, blood pressure, respiratory status of medication)
Assess (fluid and electrolyte status, medication management respect, identification, and modification)
Label/treat (arrhythmia management, reducing anxiety, anticoagulation management
Educate (disease process, anticoagulation, teaching prescribe medication’s
Define plasminogen
Thrombi constantly being formed and dissolved
Plasminogen and inactive proteins present in many body, tissues, and fluids. It is bound to fibrin, and becomes a component of the clot.
Plasminogen produces plasmin –> dissolves clot
Define arterial thrombosis
Usually associated with atherosclerotic plaque hypertension and turbulent blood flow
Define venous thrombosis
Usually associated with venous stasis
Define ischemic stroke
Stroke is characterized by sudden or progressive onset of focal neurologic signs due to inadequate blood supply to the brain
Common presenting, stroke symptoms is tingling, numbness and weakness or paralysis on one side of body in coordination aphasia changes in mental status or loss of consciousness and visual disturbances also can occur
Most off of the differences are confined to one side of the body
Symptoms of valvular, heart disease
Symptoms vary, depending on the valve that has affected
DYSPNEA is a Hallmark symptom of Michael stenosis
Dyspnea, angina, syncope in heart failure are symptoms of aortic stenosis
Mitral regurg also progressing slowly, may be asymptomatic
Each valvular disorders associated with a characteristic murmur
Native and prosthetic, valvular heart disease
Caused by degenerative valve disease due to including increasing lifespans in rheumatic heart disease
High risk for embolism antithrombotic therapy, antiplatelet therapy and anticoagulation, or a combination is warranted the most patients
Two types of heart valves, mechanical anf bioprosthetic
Number one goal of drug therapy
Providing development of a stroke. Primary goal of therapy in patients with a fib, prosthetic heart valves, and those were the history of cardioembolic stroke
Anti-cocoag treatment and patience with existing DVT/PE is to prevent extension of the thrombus, thrombolytic complications, including post thrombolytics syndrome, and development of new thrombus
Goals of drug therapy number 2
Anticoagulation prophylaxis, after orthopedic surgeries, initiated with aspirin, or anticoagulation, to decrease the risk of DVT or PE
The goals of antiplatelet therapy are to prevent and treat ischemic strokes from non-cardioEMBOLIC sources
Types of anticoagulants
Injectable agents heparin Lovenox
Oral vitamin K antagonist warfarin Coumadin

Direct acting oral anticoagulants dabigatran etexilate
Oral factor XA inhibitors apixaban rivaroxaban Eliquis and Xarelto
Antiplatelet medication
Clopidogrel plavix and ASA
Anticoagulant, injectables, and what they do
Heparin-inhibits conversion of prothrombin to thrombin and prevents thrombus formation
Low molecular weight heparin - regular heparin is processed into smaller molecules. Inactivates factor XA Lovenox.Fragmin
Fondaparinux arixta - selective inhibitor of antithrombin three and factor XA
