Defense (2) Flashcards

SImon

1
Q

Types of immune systems

A
  1. Recognition of antigens
  2. Adaptive immune system
  3. Innate immune system
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2
Q

Recognition of antigens

A

Probably evolved early

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3
Q

Adaptive immune system

A

(Vertebrates) - Antibodies which recognize antigens during reinfection

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4
Q

Innate immune system

A

(Invertebrates) - NO antibodies

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5
Q

Innate immunity def

A

Phagocytic systems enhanced by clotting - haemolymph coagulation system

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6
Q

What does the hemolymph coagulation system do?

A

– Stops spread of, and destroys bacteria
– Enhances phagocytosis
– Wound formation

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7
Q

Types of phagocytic systems enhanced by clotting

A
  • Haemolymph (haemocyte) coagulation system
  • Lectin- agglutin system
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8
Q

Lectin-agglutinin system def

A
  • sticky proteins
  • recognizes carbs (antigen molecules)
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9
Q

Induced immune system

A
  • Schistosomes
  • Fasciolids
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10
Q

Schistosomes def

A

Induced immune response - coat themselves with host antigens

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11
Q

Fasciolids def

A

Induced immune system - toxic substances

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12
Q

Internal invaders

A
  • Heat shock proteins
  • Metallothionein
  • Mixed function oxygenase
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13
Q

HSP inducers

A

Temperature - pesticides, metals, solvents

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14
Q

Metallothionein inducers

A

Metals, exhaust and smoke particles

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15
Q

Mixed function oxygenase inducers

A

Pesticides, metals, organic solvents, hydrocarbons (oil)

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16
Q

HSP function

A

– Help damaged proteins to
(re)attain their native state
– Minimise accumulation of
non-functioning or toxic
protein molecules

17
Q

Metallothioniens (MTs) def

A
  • protein that binds to h metal & detoxifies
18
Q

Mixed function oxygenase (MFO) def

A
  • Oxidize pollutants
    – Adds O2
    – Makes easier to metabolise
    – Inducible
19
Q

Mollusc MFO eg

A

Hydrocarbon pollution

20
Q

Herbivorous insects MFO eg

A

Defence toxins produced by plants

21
Q

Aging eg.

A
  • Senescene
  • Negligible senescene
  • Negative senescene
22
Q

Senescene def

A

Aging - decline in function & increase in mortality

23
Q

Negligible senescene def

A

No increase in mortality or decrease in fertility,
- physiological function or disease resistance
= can be very long lived

24
Q

Negative senescene def

A

Decline in mortality with age after reproductive maturity, usually accompanied by an increase in
fecundity
* Animals with indeterminate growth (no maximum age or
size at maturity)

25
Q

Fecundity def

A

The ability to produce an abundance of offspring or new growth; fertility

26
Q

Why does aging happen? (4)

A
  • Telomere loss theory
  • Oxidative stress/ free radical theory
  • Gene regulation theory
  • Cell turnover rate
27
Q

Telomeres def

A

Caps at the end of each strand of DNA that protect the chromosomes

28
Q

(13)

A