defects in pryimidien and purine metabolism

Question 1

lesch-nyhan syndrome

Answer 1

deficiency in hypoxanthine guanine phosphoribosyltransferase (HGP)

Question 2

hereditary orotic aciduria

Answer 2

deficiency of adenosine deaminase

Question 3

gout

Answer 3

abnormalites of purine metabolizing enzymes

Question 4

gilbert syndrome

Answer 4

decreased bilirubin diglucuronide

Question 5

5-methyl tetrahydrofolate is required for the

Answer 5

conversion of homocysteine to methionine

Question 6

In the urea cycle, citrulline is formed by the carbamoylation of

Answer 6

ornithine

Question 7

Metabolism of which of the following amino acids would be most likely to raise the level of circulating ketone
bodies in a diabetic animal?

Answer 7

leucine and lysine

Question 8

Aspartate can be synthesized by the amination of

Answer 8

oxaloacetate

Question 9

Which of the following amino acids is formed in the reaction catalyzed by arginase?

Answer 9

ornithine

Question 10

Which of the following options best describes the function of the primase enzyme in eukaryotes?

Answer 10

generation of RNA primers for use in replication