Deck 9 (slides 45-52) Flashcards

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1
Q

The Human Genome project was done using “_________ sequencing.”

A

Shotgun

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2
Q

First, cut DNA up into random _______.

A

Fragments

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3
Q

Then, determine the base sequence of each fragment using DNA sequencing (with the _______ bases).

A

Dyed

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4
Q

Then use a computer to find areas of ________ between the fragments.

A

Overlap

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5
Q

Then put the fragments together by _______ overlapping areas.

A

Linking

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6
Q

Scientists were surprised to find that only a small part of a human DNA molecule was made up of _______ (___%).

A

Genes, 2

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7
Q

They were also surprised how few genes humans had (_________).

A

20,000

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8
Q

Researchers around the world are ________ the huge amount of info in the DNA sequence; looking for genes that may provide useful clues to some of the basic properties of ______.

A

Analyzing, life

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9
Q

Biotech companies are rushing to find genetic info that may be useful in developing new drugs and treatments for ______; like _______ _______.

A

Disease, gene, therapy

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10
Q

Gene therapy is a possible way of ________ genetic disorders.

A

Curing

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11
Q

Gene therapy is the process of ________ the gene that causes the genetic defect.

A

Changing

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12
Q

The body can then make the _________ protein or enzyme it needs, which ________ the disorder.

A

Correct, eliminate

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13
Q

In _______, a young French girl was apparently cured of an inherited immune disorder.

A

1999

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14
Q

Cells from her bone _______ were removed and modified in the lab (the ________ gene was put into them); the cells were then _______ back into her body.

A

Marrow, good, placed

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15
Q

________ are often used in gene therapy because of their ability to ________ DNA into cells.

A

Viruses, inject

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16
Q

The virus is __________ so that they cannot cause disease.

A

Modified

17
Q

The replacement gene is ________ into the virus’ DNA.

A

Spliced

18
Q

The patient is then _________ with the modified virus, which should carry the gene into cells to ________ genetic defects.

A

Infected, correct

19
Q

Gene therapy experiments have not always been _________.

A

Successful

20
Q

Attempts to treat CF by ________ genetically engineered viruses into breathing passages have not produced a lasting ________, although gene therapy still holds great promise.

A

Spraying, cure