Deck 3 (slides 11-16)

Question 1

ABO blood group proteins are also found on _____ blood cells.

Answer 1

Red

Question 2

ABO blood group proteins have ____ alleles (_________ alleles).

Answer 2

3, multiple

Question 3

Multiple alleles of ABO blood group proteins shows __________.

Answer 3

Codominance

Question 4

The proteins on red blood cells are called __________.

Answer 4

Antigens

Question 5

Recessive genes for genetic diseases are on chromosomes __ - ___.

Answer 5

1-22

Question 6

Phenylketonuria (_____) is a gene on chromosome 12.

Answer 6

PKU

Question 7

PKU lacks an ________ needed to digest phenylalanine (an _______ acid).

Answer 7

Enzyme, amino

Question 8

This enzyme is found in _______ and Nutra-Sweet brand artificial sweetener (aspartame).

Answer 8

Milk

Question 9

A newborn with PKU would have phenylalanine build-up in body tissues during the first year of life, which causes severe ________ ___________.

Answer 9

Mental retardation

Question 10

Newborns can be tested for PKU and placed on a ______ phenylalanine diet that ________ the effects of PKU.

Answer 10

Low, prevents

Question 11

This is why mothers are told not to drink _______ _______ when pregnant.

Answer 11

Diet soda

Question 12

________-________ is caused be a recessive allele found mostly in Jewish families of central and Eastern European ancestry.

Answer 12

Tay-Sachs

Question 13

A person with Tay-Sachs is missing an _________ needed to break down excess _______ waste in the brain.

Answer 13

Enzyme, fatty

Question 14

In someone who has Tay-Sachs, fat builds up in the _______ resulting in the breakdown of the nervous system and _______ in the first few years of life.

Answer 14

Brain, death

Question 15

There is no _________ for Tay-Sachs.

Answer 15

Treatment

Question 16

There is a _____ for the allele of Tay-Sachs; it informs parents whether they are at ______ for having a child with Tay-Sachs; done with a DNA ______.

Answer 16

Test, risk, probe

Question 17

The most common genetic disorder for white caucasians is _________ _________ (CF).

Answer 17

Cystic Fibrosis

Question 18

Cystic Fibrosis is chased be a recessive allele on chromosome ___.

Answer 18

7

Question 19

The bad gene for Cystic Fibrosis results from the _______ of 3 DNA bases in the middle of the sequence for the protein (________ protein).

Answer 19

Deletion, CFTR

Question 20

The CFTR protein is found in cell _________ and is responsible for the passage of ____ Jon’s into the cell.

Answer 20

Membranes, Cl-

Question 21

The deletion of the 3 DNA bases causes the removal of ____ amino acid from the large CFTR protein, causing the protein to _____ improperly.

Answer 21

1, fold

Question 22

Therefore, the cells are unable to _______ Cl- ions.

Answer 22

Transport

Question 23

This results in the production of abnormally thick ______ in the lungs and digestive system.

Answer 23

Mucus

Question 24

Then, the lungs become ________ with thick mucus, causing serious lung ________.

Answer 24

Clogged, infections

Question 25

This also leads to serious _________ problems.

Answer 25

Digestive