Deck 6 - Cardiovascular Drugs Flashcards
Amount of blood ejected from the left ventricle and measured in Lpm
Cardiac Output
Resistance to blood flow
that is determined by the
diameter of the blood vessels and
vascular musculature
SVR
Drugs that accelerate the rate of urine formation that results to the
removal of sodium and water from the body
Diuretics
Acts on the brain by decreasing NE production
Central Acting
At the heart and blood vessels
Peripheral Acting
Intense but subsides within 15 mins of rest or medication and caused mainly by atherosclerosis and can be triggered by exertion or stress (cold, emotions) and
exacerbated by smoking, alcohol, coffee, and some drugs.
Chronic Stable Angina
The early stage of progressive artery disease is characterized by pain increasing in severity and frequency and may even occur at rest
Unstable Angina
From spasms of the smooth muscle that surrounds the coronary arteries and occurs at rest without any triggers but usually occur at the same time of day
Vasospastic Angina
Pathologic state in which the heart is unable to pump in sufficient amounts from the ventricles to meet metabolic needs
Heart failure
Amount of blood ejected with each contraction (65% of total ventricle volume)
Ejection fraction
Total amount of blood in the ventricle before contraction
LV End-diastolic volume
Increase the force of myocardial contraction
POSITIVE INOTROPIC drugs
Increase the rate in which the heart beats
POSITIVE CHRONOTROPIC drugs
Accelerate conduction
POSITIVE DROMOTROPIC drugs
Potent vasoconstrictor and
can prevent Na and water resorption causing diuresis
ACEI
