Deck 3 –Central Nervous System drugs Flashcards
What is the branch of pharmacology that deals with drugs that effects the nervous system?
Neuropharmacology
These are the subdivision of neuropharmacology
Autonomic and Central Nervous System
How many steps are needed in Synaptic Transmission?
5
It is used for psychiatric disorder, suppression or prevention of seizures, mood stabilizers, pain relief, and anesthesia.
CNS Drugs
CNS contains how many compounds that serves as neurotransmitter?
21
What does the blood brain barrier do?
Protects brain form injury
Prevents sudden burst of braincells
Limits passage of soluble agents
Which are more sensitive to CNS drugs? Adults or Children? Why?
Children because their blood brain barrier is not fully developed
Tolerance, Physical Dependance, Increased Therapeutic Effects, and Decreased side effects are part of what?
Adaptations to prolonged drug use of CNS Drugs
What do you mean by ADHD?
Attention Deficit/ Hyperactivity Disorder
When do you diagnose ADHD?
It is common for children when it disrupts the daily activity or causes injury and harm.
What are 2 drugs under amphetamines that are useful for patients with ADHD and narcolepsy?
Methylphenidate
Modafinil
2 drugs for patients with respiratory depression or COPD
Xanthine
Doxa pram
What should be the intervention to patients who has COPD or difficulty of breathing because of depressed respiration?
Up to 3L oxygenation only
It is a chronic and progressive disorder that initially causes tremor, stiffness or postural inability, and slow movement.
Parkinson’s disease
What results in lower dopamine?
Disturbed movement
What should you do if dopamine is lower than acetylcholine?
Give higher dose of dopamine or decrease amount of acetylcholine
Carbidopa should always be partnered with what drug?
Levodopa
What is the purpose of COMT INHIBITORS?
Supports the Levodopa by inhibiting its breakdown
What diseases can dopamine releaser take effect?
HIV, respiratory viruses, Influenza
What happens when Levodopa combined with MAOI? This is also a health teaching that you should remember.
It causes Hypertensive crisis