Deck 3 – Central Nervous System drugs Flashcards
NEUROPHARMACOLOGY is
A study of drugs that alter processes controlled by the nervous system.
How neurons regulate other cells?
Conducting an action potential down the axon of the neuron.
Synaptic Transmission -
Process by which information is carried across the gap between neuron and postsynaptic cell.
What is CNS drugs used for?
It is used for psychiatric disorders, suppression of seizures, relief of pain, production of anesthesia.
What is the role of BLOOD BRAIN
BARRIER?
It impedes the entry of drugs into the
brain.
What is CNS STIMULANTS used for?
Attention deficit disorder(ADHD), narcolepsy or excessive sleepiness.
Characteristics: inattentiveness, inability to concentrate, restlessness, hyperactivity, inability to complete tasks and impulsivity.
ADHD [Attention Deficit/ Hyperactivity Disorder].
Characterized by falling asleep during normal waking activities[driving ,talking].
And unable to move and may collapse.
NARCOLEPSY.
Analeptics: Xanthine is a treatment for?
Respiratory depression caused by
drug overdose and COPD.
It is a drug given to increase child’s attention span and cognitive
performance.
And also used to treat narcolepsy.
Methylprenidate.
It is a disease which slowly progressive neurodegenerative disorder characterized by tremor, rigidity,
postural instability and slowed movement.
PARKINSON’S DISEASE.
It directly/ indirectly cause
activation of dopamine receptors.
Dopaminergic drugs.
Anticholinergic Agents is a drug
that block receptors for ACh.
The Mechanism action of this drug is inhibits breakdown of levodopa.
COMT INHIBITORS:
Entacapone
& tolcapone.
It is a Group of disorders characterized
by excessive excitablility of neurons in the CNS.
• SEIZURE – general term that apllies to all types of epileptic events.
• CONVULSION – abnormal motor phenomenon.
EPILEPSY.
It is commonly prescribed anticonvulsant drug to stabilize nerve cells to keep them from getting overexcited by increasing efflux or decreasing influx of sodium ions.
PHENYTOIN.
