Deciding what is normal and interpreting a blood count Flashcards
What affects what is normal?
Age Gender Ethnic origin Physiological status Altitude Nutritional status Cigarette smoking and alcohol intake
What is normal distribution known as?
Gaussian
What sort of distribution does Hb and WBC show?
Hb- Gaussian
WBC- Non-Gaussian
What is packed cell volume and haematocrit measured in?
l/l
What is mean cell volume measured in?
fl
What is mean cell haemoglobin measured in?
pg
What is the definition for mean cell haemoglobin?
Amount of haemoglobin in a given volume of blood divided by number of red cells in same volume- Hb divided by RBC
What is the definition for mean cell haemoglobin concentration?
Amount of haemoglobin in a given volume of blood divided by the proportion of the sample represented by the red cells- Hb divided by PCV or haematocrit
What is the difference between MCH and MCHC?
MCH is absolute amount of haemoglobin in an individual red cell
MCHC is concentration of haemoglobin in a red cell- related to shape of cell
How is MCHC measured?
Electronically using light scattering