DBS

Question 1

Target for Dystonia DBS

Answer 1

GPi

Question 2

Which cardinal symptom of PD does not improve well with DBS?

Answer 2

Gait and balance

*Non-axial symptoms: Tremor, Rigidity and Bradykinesia improve with DBS

Question 3

T/F. Speech worsens with DBS

Answer 3

True esp. with STN DBS

Question 4

T/F. Cognition is not worsened by DBS in general.

Answer 4

True but if cognition is not intact prior to DBS, cognition may worsen.

Question 5

Ideal age for DBS

Answer 5

<65

Question 6

Who is the ideal DBS candidate?

Answer 6

Severely disabled in the OFF condition, independent in the ON condition

Question 7

Which target is avoided if patient has MCI?

Answer 7

STN.

GPi or unilateral procedure may be done in selected cases.

Question 8

T/F. ICD and DDS don’t usually improve and may even get worse with DBS.

Answer 8

True

Question 9

Which target shows better improvement in Motor Function and has more reduction in LEDD?

Answer 9

STN DBS while both STN and GPi have the same amount of improvement for dyskinesias.

Question 10

Match the patient profile with DBS target: STN or GPi

1. Responds to lower doses of LD but has low threshold for dyskinesias
2. Uses higher doses of LD
3. Experiences disabling side effects of dopaminergic treatment
4. Has LD responsive non-motor signs

Answer 10

1. GPi
2. STN
3. STN
4. GPi

Question 11

T/F. VIM DBS is more likely to induce dysphagia and dysarthria.

Answer 11

True

Question 12

Target for DBS in dystonia

Answer 12

GPi

Question 13

Which symptom of CD usually improves first with DBS?

Answer 13

Blepharospasm whereas speech and swallowing may not change.

Question 14

DBS is usually less effective for Secondary dystonia except for

Answer 14

Tardive dystonia