Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MCM > Day 1 & 2 > Flashcards

Day 1 & 2 Flashcards

1
Q

Formed by mainly alpha helices and hydrophobic amino acids

A

Transmembrane domains

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Heat shock protein that prevents premature folding

A

HSP70

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Heat shock protein that folds the protein using ATP

A

HSP60

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Causes lung and liver problems by aggregating in the ER

A

alpha1-antitrypsin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Protein misfolding that has excessive Beta sheets

A

Creutzfeld-Jacob or Amyloidosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Serum amyloid A fragments

A

Rheumatoid arthritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

antibody Light chain fragments

A

Multiple myeloma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Beta-amyloid fragments

A

Alzheimer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Oxygen radicals in RBCs; causes heinz bodies

A

G6P dehydrogenase deficiency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Used in assessing LUNG MATURITY of fetus

A

Choline (Lecithins)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Most common polar head in plasmalogens

A

Ethanolamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Lipid that plays a role in apoptosis signaling; Annexin V assay

A

Serine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Essential in the synthesis of secondary messengers

A

Inositol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Used to assess FETAL LUNG DEVELOPMENT

A

Glycerol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cholesterol _____ are completely hydrophobic

A

Esters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Causes the indent in RBCs, spherocytosis

A

Spectrin and Ankyrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Enzyme that transfers electrons

A

Oxidoreductases(dehydrogenases)

18
Q

Add or remove atoms (without ATP)

A

Lyases

19
Q

Forms bonds (with ATP)

A

Ligases

20
Q

Non-protein component of an enzyme that is tightly bound

A

Prosthetic group

21
Q

Non-protein component of an enzyme that is loosely bound

A

Coenzyme

22
Q

Forms covalent bond with substrate

A

Activation-transfer

23
Q

Does not form covalent bond with substrate

A

Oxidation-reduction

24
Q

Deficiency in thiamine pyrophosphate results in

A

Beriberi

25
Q

Zinc containing enzyme that oxidizes ethanol

A

Alcohol dehydrogenase

26
Q

Required for kinases to bind phosphate groups

A

Magnesium

27
Q

Target of penicillin (transition state inhibitor)

A

Glycopeptidyl transferase

28
Q

Allopurinol targets (transition state inhibitor)

A

Xanthine oxidase

29
Q

Organophosphorous covalently binds to

A

Acetylcholinesterase

30
Q

Metal ion that causes anemia

A

Aluminum

31
Q

Covalently acetylates active site of COX-1

A

Aspririn

32
Q

Isoenzyme of glucose metabolism that has higher affinity (RBCs)

A

Hexokinase

33
Q

Competitive inhibitor of HMG-CoA reductase

A

Statins

34
Q

Decreases Km, Vmax stays the same

A

Competitive

35
Q

Decreases Vmax, Km stays the same

A

Non-competitive

36
Q

Decreases Vmax and Km

A

Uncompetitive

37
Q

Decreases Vmax, Km unchanged (Long term)

A

Irreversible

38
Q

Allosteric inhibition is a form of _______ inhibition

A

noncompetitive

39
Q

Going from taut to relaxed in cooperativity

A

Increases affinity

40
Q

Lysine and arginine are targets of

A

ADP-Ribosylation

41
Q

cAMP usually ________ protein kinase A

A

Phosphorylates

MCM (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions