dating endometrium

Question 1

gland mitoses and tortuosity

Answer 1

• gland mitoses indicates proliferation

- they occur during menstruation because repair and breakdown are progressing simultaneously then

Question 2

pseudostratification of the nuclei

Answer 2

• characteristic of the proliferation phase but persists until active secretion begins
• its not resumed until the glands have involuted during menstruation

Question 3

basal vacuolation

Answer 3

this is the earliest morphological evidence of ovulation found in the endometrium

• it begins approx 36-48 hours following ovulation
• peaks at day 17 (beginning of secretion

Question 4

secretion

Answer 4

• curve represents visible secretion in the gland lumen

- active secretion falls off more abruptly

Question 5

stromal edema

Answer 5

• varies with individuals, particularly the rise during proliferation which may be almost absent
• the edema which accompanies secretion is more constant
• small rise at mid-proliferation

Question 6

pseudodecidual reaction

Answer 6

this is evident first around the arterioles and progresses until just before menstruation a superficial compact layer is formed
- rise at the end of secretion

Question 7

stromal mitoses

Answer 7

• most abundant during the proliferative phase, absent during active secretion but reaper during the stage of pre-decidual formation (end of secretion)

Question 8

leucocytic infiltration

Answer 8

• throughout the cycle there are always a few lymphocytes
• polymorphonuclear infiltration begins about 2 days before the onset of flow (day ~24)
• appears prior to menstruation for protection