DAT ch 8 sn1 sn2 e1 e2 Flashcards
TSO TFO and mso are what
leaving groups
you can have a leaving group on a sp2 carbon t/f
false
what are good leaving groups
halogens.
increasing size the better
strong nucleophiles
M-cn M-OR M-Oh M-Sr M-NR2 M-R
M= metals likes Li, Na, K, Or Mg
So when you see metals just cross them out and replace them with a negative charge.
weak nucleophiles
Rco2- HOR H20 HSR HNR2
R= alkyl or H
E2 always follows zaitsevs rule except or when
a bulky base is used like t butoxide CH3)3Co-
is E2 protic or aprotic
aprotic preferred
is E1 protic or aprotic
protic
Is Sn2 aprotic or protic
aprotic preferred
is Sn1 protic or aprotic
protic
Exception where Sn2 can do protic
When an alkoxide base (CH30-) is paired with their conjugate acid CH3OH (protic solvent ) so when these two things are written together…… sn2 can occur in protic solvent