D/D Medications (Exam 2)

Question 1

Medications to Treat Dementia

Answer 1

-Cholinesterase Inhibitor (Donepezil)

-N-methyl-Daspartate (NMDA) receptor antagonist (Memantine)

(expensive)

Question 2

Donepezil: Class

Answer 2

-Cholinesterase Inhibitor

Question 3

Donepezil: MOA

Answer 3

-Works centrally in the brain to increase levels of acetylcholine by inhibiting acetylcholinesterase

Question 4

Donepezil: Indications

Answer 4

-Mild to moderate AD

Question 5

Donepezil: Adverse Effects

Answer 5

-drowsy

Question 6

What should you not take with Donepezil

Answer 6

-NSAID’s

-Could compound the GI risk

Question 7

Donepezil: Nursing Consideration

Answer 7

-Give PO at bedtime, best with food to minimize GI effects

Question 8

Memantine: Class

Answer 8

-N-methyl-Daspartate (NMDA) receptor antagonist

Question 9

Memantine: MOA

Answer 9

-Blocks the stimulation of NMDA receptors believed to be associated with AD

Question 10

Memantine: Indications

Answer 10

-Moderate-severa AD

Question 11

Memantine: Adverse effects

Answer 11

-Constipation (TAKE FIBER AND STOOL SOFTENER)