D-D-I Decongestants Flashcards
What potential interaction is associated with Decongestants and Ergot derivatives (e.g., dihydroergotamine and ergotamine)?
Increased risk of hypertension and vasoconstriction. Avoid combination.
What potential interaction is associated with Decongestants and Linezolid?
Increased risk of hypertension. Reduce the dose of decongestant and monitor closely. Consider therapy modification.
What potential interaction is associated with Decongestants and MAOIs (e.g., phenelzine, selegiline)?
Increased risk of hypertension. Avoid combination.
What potential interaction is associated with Decongestants and Serotonin/norepinephrine reuptake inhibitors?
Increased risk of tachycardia. Consider therapy modification.
What advice should pharmacists give to pregnant or lactating women regarding product labels?
Avoid products labeled “extra strength,” “maximum strength,” or “long-acting,” as well as combination products.
Why should systemic decongestants be avoided during pregnancy?
Human data suggests an increased risk of adverse effects due to decreased fetal blood flow.
What is the association between oral phenylephrine use during the first trimester and malformations?,
It has been associated with minor malformations such as inguinal hernia or congenital hip dislocation.
What birth defect is linked to pseudoephedrine use during pregnancy?
What is the preferred topical decongestant during pregnancy?, Oxymetazoline, which is poorly absorbed after intranasal administration.
Do nonprescription cold products affect male reproductive function?,No, they do not appear to have an impact on male reproductive function.
Abdominal wall defects (gastroschisis) in newborns.
What is the preferred topical decongestant during pregnancy?
Oxymetazoline, which is poorly absorbed after intranasal administration.
Do nonprescription cold products affect male reproductive function?
o, they do not appear to have an impact on male reproductive function.
