COUGH-TOPICAL NASAL DECONGESTANTS Flashcards
What is the trade name of the product with the primary ingredient Oxymetazoline HCl 0.05%
,Afrin Original Nasal Spray
What is the trade name of the product with the primary ingredient Oxymetazoline HCl 0.05%
,Vicks Sinex Nasal Spray
What is the trade name of the product with the primary ingredient Phenylephrine HCl 1%
,4-Way Fast Acting
What is the trade name of the product with the primary ingredient Phenylephrine HCl 0.25%
,Neo-Synephrine Mild Strength Nasal Spray
What is the trade name of the product with the primary ingredient Phenylephrine HCl 0.125%
,Little Remedies Decongestant Nose Drops
What is the trade name of the product with the primary ingredient Xylometazoline 0.1%
,Otrivin Medicated Cold & Nasal Spray
What is the primary ingredient of Afrin Original Nasal Spray
,Oxymetazoline HCl 0.05%
What is the primary ingredient of Vicks Sinex Nasal Spray
,Oxymetazoline HCl 0.05%
What is the primary ingredient of 4-Way Fast Acting
,Phenylephrine HCl 1%
What is the primary ingredient of Neo-Synephrine Mild Strength Nasal Spray
,Phenylephrine HCl 0.25%
What is the primary ingredient of Little Remedies Decongestant Nose Drops
,Phenylephrine HCl 0.125%
What is the primary ingredient of Otrivin Medicated Cold & Nasal Spray
,Xylometazoline 0.1%
What is the recommended dosage for Ephedrine 0.5% in adults and children ≥ 12 years
,2–3 drops/sprays in each nostril not more often than every 4 hours
What is the recommended dosage for Ephedrine 0.5% in children 6 to < 12 years
,1–2 drops/sprays in each nostril not more often than every 4 hours
What is the recommended dosage for Ephedrine 0.5% in children 2 to < 6 years
,Not recommended for children <6 years except under advice of HCP
What is the recommended dosage for Levmetamfetamine 0.04–0.15 mg/800 mL of air in adults
,2 inhalations in each nostril not more often than every 2 hours
What is the recommended dosage for Levmetamfetamine 0.04–0.15 mg/800 mL of air in children 6 to < 12 years
,1 inhalation in each nostril not more often than every 2 hours
What is the recommended dosage for Levmetamfetamine 0.04–0.15 mg/800 mL of air in children 2 to < 6 years
,Not recommended for children <6 years except under advice of HCP
What is the recommended dosage for Naphazoline 0.05% in adults
,1–2 drops/sprays in each nostril not more often than every 6 hours
What is the recommended dosage for Naphazoline 0.05% in children 6 to < 12 years
,Not recommended for children <12 years except under advice of HCP
What is the recommended dosage for Naphazoline 0.05% in children 2 to < 6 years
,Not recommended for children <6 years except under advice of HCP
What is the recommended dosage for Oxymetazoline 0.05% in adults and children ≥ 12 years
,2–3 drops/sprays in each nostril not more often than every 10–12 hours (maximum: 2 doses/ 24 hours)
What is the recommended dosage for Oxymetazoline 0.05% in children 6 to < 12 years
,2–3 drops/sprays in each nostril not more often than every 10–12 hours (maximum: 2 doses/ 24 hours)
What is the recommended dosage for Oxymetazoline 0.05% in children 2 to < 6 years
,Not recommended for children <6 years except under advice of HCP
What is the recommended dosage for Phenylephrine 1.0% in adults
,2–3 drops/sprays in each nostril not more often than every 4 hours
What is the recommended dosage for Phenylephrine 1.0% in children 6 to < 12 years
,Not recommended for children <12 years except under advice of HCP
What is the recommended dosage for Phenylephrine 1.0% in children 2 to < 6 years
,Not recommended for children <6 years except under advice of HCP
What is the recommended dosage for Phenylephrine 0.5% in adults
,2–3 drops/sprays in each nostril not more often than every 4 hours
What is the recommended dosage for Phenylephrine 0.5% in children 6 to < 12 years
,2–3 drops/sprays in each nostril not more often than every 4 hours
What is the recommended dosage for Phenylephrine 0.5% in children 2 to < 6 years
,Not recommended for children <6 years except under advice of HCP
What is the recommended dosage for Phenylephrine 0.25% in adults
,2–3 drops/sprays in each nostril not more often than every 4 hours
What is the recommended dosage for Propylhexedrine 0.4–0.5 mg/800 mL of air in adults
,2 inhalations in each nostril not more often than every 2 hours
What is the recommended dosage for Propylhexedrine 0.4–0.5 mg/800 mL of air in children 6 to < 12 years
,2 inhalations in each nostril not more often than every 2 hours
What is the recommended dosage for Propylhexedrine 0.4–0.5 mg/800 mL of air in children 2 to < 6 years
,Not recommended for children <6 years except under advice of HCP
What is the recommended dosage for Xylometazoline 0.1% in adults
,2–3 drops/sprays in each nostril not more often than every 8–10 hours
What is the recommended dosage for Xylometazoline 0.1% in children 6 to < 12 years
,Not recommended for children <12 years except under advice of HCP
What is the recommended dosage for Xylometazoline 0.1% in children 2 to < 6 years
,Not recommended for children <6 years except under advice of HCP
What is the recommended dosage for Xylometazoline 0.05% in adults
,2–3 drops/sprays in each nostril not more often than every 8–10 hours
What is the recommended dosage for Xylometazoline 0.05% in children 6 to < 12 years
,2–3 drops/sprays in each nostril not more often than every 8–10 hours (maximum: 3 doses/ 24 hours)
What is the recommended dosage for Xylometazoline 0.05% in children 2 to < 6 years
,Not recommended for children <6 years except under advice of HCP
What is the dosage for adults and children ≥ 12 years of Ephedrine 0.5%
,2–3 drops/sprays in each nostril not more often than every 4 hours
What is the dosage for children 6 to < 12 years of Ephedrine 0.5%
,1–2 drops/sprays in each nostril not more often than every 4 hours
What is the dosage for children 2 to < 6 years of Ephedrine 0.5%
,Not recommended for children <6 years except under advice of HCP
What is the dosage for adults of Levmetamfetamine 0.04–0.15 mg/800 mL of air
,2 inhalations in each nostril not more often than every 2 hours
What is the dosage for children 6 to < 12 years of Levmetamfetamine 0.04–0.15 mg/800 mL of air
,1 inhalation in each nostril not more often than every 2 hours
What is the dosage for children 2 to < 6 years of Levmetamfetamine 0.04–0.15 mg/800 mL of air
,Not recommended for children <6 years except under advice of HCP
What is the dosage for adults of Naphazoline 0.05%
,1–2 drops/sprays in each nostril not more often than every 6 hours
What is the dosage for children 6 to < 12 years of Naphazoline 0.05%
,Not recommended for children <12 years except under advice of HCP
What is the dosage for children 2 to < 6 years of Naphazoline 0.05%
,Not recommended for children <6 years except under advice of HCP
What is the dosage for adults and children ≥ 12 years of Oxymetazoline 0.05%
,2–3 drops/sprays in each nostril not more often than every 10–12 hours (maximum: 2 doses/ 24 hours)
What is the dosage for children 6 to < 12 years of Oxymetazoline 0.05%
,2–3 drops/sprays in each nostril not more often than every 10–12 hours (maximum: 2 doses/ 24 hours)
What is the dosage for children 2 to < 6 years of Oxymetazoline 0.05%
,Not recommended for children <6 years except under advice of HCP
What is the dosage for adults of Phenylephrine 1.0%
,2–3 drops/sprays in each nostril not more often than every 4 hours
What is the dosage for children 6 to < 12 years of Phenylephrine 1.0%
,Not recommended for children <12 years except under advice of HCP
What is the dosage for children 2 to < 6 years of Phenylephrine 1.0%
,Not recommended for children <6 years except under advice of HCP
What is the dosage for adults of Phenylephrine 0.5%
,2–3 drops/sprays in each nostril not more often than every 4 hours
What is the dosage for children 6 to < 12 years of Phenylephrine 0.5%
,2–3 drops/sprays in each nostril not more often than every 4 hours
What is the dosage for children 2 to < 6 years of Phenylephrine 0.5%
,Not recommended for children <6 years except under advice of HCP
What is the dosage for adults of Phenylephrine 0.25%
,2–3 drops/sprays in each nostril not more often than every 4 hours
What is the dosage for adults of Propylhexedrine 0.4–0.5 mg/800 mL of air
,2 inhalations in each nostril not more often than every 2 hours
What is the dosage for children 6 to < 12 years of Propylhexedrine 0.4–0.5 mg/800 mL of air
,2 inhalations in each nostril not more often than every 2 hours
What is the dosage for children 2 to < 6 years of Propylhexedrine 0.4–0.5 mg/800 mL of air
,Not recommended for children <6 years except under advice of HCP
What is the dosage for adults of Xylometazoline 0.1%
,2–3 drops/sprays in each nostril not more often than every 8–10 hours
What is the dosage for children 6 to < 12 years of Xylometazoline 0.1%
,Not recommended for children <12 years except under advice of HCP
What is the dosage for children 2 to < 6 years of Xylometazoline 0.1%
,Not recommended for children <6 years except under advice of HCP
What is the dosage for adults of Xylometazoline 0.05%
,2–3 drops/sprays in each nostril not more often than every 8–10 hours
What is the dosage for children 6 to < 12 years of Xylometazoline 0.05%
,2–3 drops/sprays in each nostril not more often than every 8–10 hours (maximum: 3 doses/
Question,Answer
What are the advantages of nasal sprays as a delivery form?
imple to use, cover a large surface area, relatively inexpensive, and have a fast onset of action.
What are the disadvantages of nasal sprays as a delivery form?
Imprecise dosage, a tendency for the tip to become clogged with repeated use, and a high risk of contamination from aspiration of nasal mucus into the bottle.
What are the advantages of metered pump sprays as a delivery form?
Deliver a more precise dose.
What are the advantages of nasal drops as a delivery form?
Preferred for small children.
What are the disadvantages of nasal drops as a delivery form?
Can be difficult to use, cover a limited surface area, and pass easily into the larynx. A high risk of contamination from touching the dropper to the nasal mucosa during administration is also recognized.
What are the advantages of nasal inhalers as a delivery form?
Small and convenient to use.
What are the disadvantages of nasal inhalers as a delivery form?
Require an unobstructed airway and sufficient air flow to distribute the drug to the nasal mucosa. Lose efficacy after 2–3 months due to dissipation of the active ingredien
What factors have been shown to be associated with reduced efficacy of topical nasal dosage forms?
Presence of nasal polyps, enlarged turbinates, and abnormalities such as septal deviation.
