cytology questions Flashcards

1
Q

Which of the following is not included in the glycocalyx?

A

steroids

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2
Q

Organelles involved in rectory pathway?

A

All are true except peroxisomes

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3
Q

Electrically excited cells are?

A

All are true except adipocytes.

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4
Q

Which substances are detected by periodic acid shift PAS staining method?

A

Glycolipids & Glycoproteins

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5
Q

Which of the following are inorganic compounds of the cell?

A

water

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6
Q

Microtubules..which of the following statement is true?

A

Have a wall composed of 13 protofilament.

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7
Q

Which of the following statements regarding lysosomes is true?

A

Optimal pH is 5.0

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8
Q

The middle segment of chromosomes is known as

A

centromere

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9
Q

. All of the following cell junctions are associated with the cytoskeleton except

A

nexus(gap) junctions

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10
Q

. Synaptical vesicles..are all true except?

A

Do not have a membrane.

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11
Q

Cytoskeleton motor proteins are..all are true except

A

Vimentin

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12
Q

The division of the nucleus is reffered to as

A

Mitosis

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13
Q

Where the fibres of the nuclear lamina localised?

A

Just inside the inner nuclear membrane

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14
Q

Which of the following regarding cell shape is not true

A

Smooth muscle cells are cuboidal cells

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15
Q

Integrins are..all are true except

A

Intermediate filament receptors.

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16
Q

All of the following structures contain microtubules except

A

Microvilli

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17
Q

. All of the following are cell to cell junctions except

A

hemidesmosome

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18
Q

Which statement regarding peroxisomes is true

A

Peroxisomes are generated from pre-existing peroxisomes.

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19
Q

Secretory granules..all are true except

A

Are returned to the Rough ER for recycling

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20
Q

Which is the range of thickness of the biological membranes?

A

5-10µm

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21
Q

F-actin is found in

A

microfilaments

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22
Q

Components of the nuclear envelope..all are true except

A

chromatin

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23
Q

Which of the following statements related to the Golgi Complex is not true?

A

? It is a semi autonomous organelle that contains DNA, RNA & Ribosomes.

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24
Q

Autophagosomes are typical for

A

lymphocytes

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25
Q

The cytosol..which of the following statements is not true

A

Contains ions and small proteins

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26
Q

Intermediate filaments are composed of

A

keratin

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27
Q

Synaptic vesicles..all are true except?

A

Use microtubules for their movement

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28
Q

Smooth ER is not involved in

A

Protein synthesis

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29
Q

Ribosomes can attach to which of the following?

A

Outer nuclear membrane

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30
Q

Ca2+ release from the endoplasmic reticulum takes place via

A

Voltage sensitive Ca2+ channels

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31
Q

Extracellular proteins such as hormones achieve their effect on the cells by the means of

A

Transmembrane receptors

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32
Q

Secretory proteins..all are true except?

A

Are translocated into the nucleus.

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33
Q

Which of the cells have a prominent rough ER?

A

Adrenal gland cells.

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34
Q

The parts of DNA which are not exposed are concentrated in..?

A

Heterochromatin

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35
Q

. Amino-oxidase and catalase are characteristic enzymes of..?

A

peroxisomes

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36
Q

. Microtubules..all are true except?

A

Are the thick filaments of the sarcomere

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37
Q

Intermediate filaments are associated with which of the following cell junctions

A

desmosomes

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38
Q

. Organelle included in the secretory pathway..All are true except

A

peroxisomes

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39
Q

Which of the following is not a component of the plasma membrane?

A

nucleic acids

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40
Q

Which of the following substance is not a component of the biomembrane?

A

melanin

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41
Q

Microfilaments

A

Consist of globular actin monomers forming a double helix

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42
Q

Which of the following of the cell matrix function is true?

A

Regulates intracellular traffic of the molecule

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43
Q

Which of the following statements regarding the Golgi Complex is true?

A

It is the site of protein glycosylation

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44
Q

Intracellular targeting of vesicles depends on?

A

Snare-Snare Interactions

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45
Q

The Barr-body corresponds to?

A

Heterochoromatin

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46
Q

Integrins

A

Link the Extracellular Matrix with the Cytoskeleton

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47
Q

The chromatin contains the following elements..All are true except

A

RNA

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48
Q

Microtubules..all are true except

A

Associate with myosin

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49
Q

Major mitochondrial compartments are..All are true except

A

mitochondrial pores

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50
Q

Which of the following is not a characteristic of living matter?

A

refraction

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51
Q

Tissues grow in site because of the following processes..All are true except

A

apoptosis

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52
Q

Ageing is associated with which type of processes..All are true except

A

hyperplasia

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53
Q

The main molecular railroads for intracellular transport are

A

microtubules

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54
Q

Biological membranes..Which of the following is not true?

A

Organise the mitotic spindle during cell division

55
Q

Which of the following statements about cell matrix functions are true?

A

It regulates intracellular traffic of molecules and organelles.

56
Q

The cytoplasmic inclusions

A

all answers are correct

57
Q

Ribosomes are..All are true except

A

related in function to lipid synthesis

58
Q

Apoptosis is..All are true except

A

A spontaneous process.

59
Q

Cell crystals

A

Crystalline forms of protein

60
Q

Which family of proteins are excretions of apoptosis?

A

capsases

61
Q

Which of the following statements related to histological techniques is not true?

A

Paraffin embedding includes processing of the material

62
Q

Which of the following about eukaryotic/prokaryotic cells is not true?

A

Prokaryotic cells are cells with a nuclear envelope

63
Q

All of the following statements regarding pigment deposits are true except?

A

globin is a pigment

64
Q

Movement of which type of particle is involved in the generation of ATP?

A

proton

65
Q

Signal recognition particle/SR receptors are required for the translocation of

A

secretory proteins

66
Q

Cells participating in closing the wound

A

myofibroblast

67
Q

Which cell type has a squamous shape

A

endothelial cells

68
Q

Which of the following statements about plasmalemma is true?

A

Ion channels are transmembrane proteins.

69
Q

Which of the following membrane proteins are not localised in the plasma membrane?

A

histone molecules

70
Q

Which of the cell types have more than one nucleus? All are true except

A

Neutrophil Leukocytes

71
Q

Which of the following statements about lysosomes is not true

A

Optimal pH of lysosomal digestion is pH 8.0

72
Q

Which of the following molecules are material carrier of life?

A

Protein & Nucleic acids

73
Q

Golgi Complex-RER communication requires

A

COP coated vesicles

74
Q

Clathrin coated vesicles are formed in

A

transgolgi network

75
Q

The change of cell shape requires which following organelles

A

actin filaments

76
Q

Which is the size range for peroxisomes?

A

0.5-1.5mm

77
Q

Which of the cytoskeletal proteins is components of nuclear lamina?

A

intermediate filaments

78
Q

Secretory proteins

A

Are not translocated into the RER

79
Q

Which type of molecules can pass through the nuclear pore?

A

Molecules with a nuclear localisation signal

80
Q

Which phase of the mitotic cycle is mediated by actin cytoskeleton?

A

cytokenesis

81
Q

Which of the following does not belong to cytoplasmic inclusions?

A

secretory vesicles

82
Q

The Zelwegger syndrome is related to biogenesis of which organelle?

A

peroxisomes

83
Q

Which of the following statements regarding the structure of biomembranes is true?

A

Biomembranes are supermolecular lipoprotein complexes composes of polar lipids and proteins

84
Q

The process of apoptosis normally occurs

A

during mitotic cell death

85
Q

Secretory granules are characteristic for

A

exocrine cells

86
Q

Mitochondrial ATP synthase is involved in

A

oxidative phosphorylation

87
Q

What is the main function of the intermediate filaments?

A

structural stability of the cell

88
Q

Which of the following are non membranous?

A

microtubules

89
Q

Which of the following statement about the cell theory is not true?

A

There is no close relationship between cell structure and function

90
Q

Which of the following is a market enzyme for lysosomes?

A

Acid phosphitase

91
Q

.Components of the mitotic spindle are, all true except

A

actin filaments

92
Q

Ribosomes can attach to which of the following

A

outer nuclear membrane

93
Q

Which of the following statements is not true?

A

Proteins contain glycerol, fatty acids and ATP

94
Q

Which of the following structures (centriole) is true?

A

Each centriole is composed of 9 microtubule triplets and 0 in the centre

95
Q

Which of the following increases surface area necessary for absorption?

A

microvilli

96
Q

Which of the following about the plasma membrane is not true?

A

It maintains the negative charge of the cell surface.

97
Q

Free poly-ribosomes synthesize proteins for

A

cytosol

98
Q

Which of the following ions is not present in the cytosol?

A

Hg2

99
Q

Divisions of tissue stem cells result from direct activity of

A

DNA molecules

100
Q

The role of Calcium is muscle contraction is

A

To bind to troponin and expose actin filaments to myosin heads

101
Q

How many centrioles are there in non dividing cells?

A

2

102
Q

The kinetic core binds to which segment of the chromosome?

A

centromere

103
Q

Glycogen granules

A

Are responsible for Glucose storage

104
Q

Which of the following methods uses a beam of electrons?

A

Transmission Electron Microscope

105
Q

Which cells have plenty of lysosomes?

A

phagocytes

106
Q

Molecules involved in the transmembrane transport of small molecules (small than 1000) are all true except?

A

hormone receptors

107
Q

Which is the range of size of human cells?

A

5-200 mm

108
Q

What is the normal pathway of migration of proteins through the Golgi Apparatus?

A

? Cis golgi –> Oyctiosomes –> Trans golgi –> Trans golgi: Network

109
Q

Which of the following is not a function of EPR?

A

Microtubule organiser

110
Q

Major mitochondrial functions are all true except

A

phagocytosis

111
Q

Which of the following molecules are present in the cytosol?

A

H20

112
Q

Which of the following molecules are not carbohydrates?

A

polypeptides

113
Q

What are the main components of the nucleus?

A

all answers are correct

114
Q

Cell movement requires

A

microtubules

115
Q

Cell differentiation includes the following features. All are true except

A

apoptosis

116
Q

Which of the following statements related to the RER is true?

A

It takes part in the metabolism of glycogen

117
Q

The diameter of actin filament is

A

6-8nm

118
Q

Which of the following statements relating to H&E staining is true?

A

Basophilic structures under H&E stain are not red

119
Q

Where are intermediate filaments present?

A

in the nucleus and cytosol

120
Q

The brushborder of erythrocytes represents which structure?

A

microvilli

121
Q

The glycocalyx is composed of all, except?

A

glyocolipids

122
Q

Microtubules are found in the

A

microvilli

123
Q

What is the function of dystropin?

A

It links microfilaments to the plasmalemma

124
Q

What syndrome is the genetic defect in Dynein linked to?

A

Kartagener syndrome

125
Q

What is the function of the layer at the bottom (usually pointed with an arrow) of the plasmalemma?

A

ion transport

126
Q

The caveolae are involved in all except

A

ATP synthesis

127
Q

Which of the following answers is TRUE

The viscous external surface cover of the plasmalemma is called?

A

glycocalyx

128
Q

Which cytoskeleton is associated with the hemidesmosome?

A

Intermediate filament

129
Q

Which of the following cytoskeletal elements is important for the nucleus?

A

intermediate filaments

130
Q

Which cytoskeleton is associated with the adherent junction?

A

actin filements

131
Q

What type of cell junction is the adherent junction?

A

cell-cell

132
Q

Which cytoskeleton is associated with the desmosome?

A

intermediate filament

133
Q

Which of the listed proteins does not interact with actin filament?

A

kinesin

134
Q

which cytoskeleton is associated with focal adhesion?

A

Actin Filament