Cytology

Question 1

cytological classification of salivary gland lesions and description

Answer 1

Milan classification

Consists of 6 diagnostic categories:
Nondiagnostic
- Insufficient cellular material: less than 60 lesional cells for a cytologic diagnosis
- Nonneoplastic acinar cells only in the setting of a clinically defined nodule
- Nonmucinous cyst fluid only
- Poorly prepared slides with artifacts (ex: air drying, obscuring blood, poor staining, etc.)

Nonneoplastic
- Benign nonneoplastic conditions (ex: sialadenitis, sialolithiasis, granulomatous inflammation, infection, reactive lymph node, etc.)

Atypia of undetermined significance (AUS)
- Limited cellular atypia
- Lacks qualitative or quantitative features for diagnosing a neoplasm

Neoplasm (benign and salivary gland neoplasm of uncertain malignant potential [SUMP])
- Characteristic cytomorphologic features of a specific benign neoplasm OR
- Cytomorphologic features diagnostic of a neoplasm but indefinite for a specific tumor type to further distinguish between benign or malignant

Suspicious for malignancy (SM)
-Features that are highly suggestive of but not unequivocal for malignancy

Malignant
- FNA showing diagnostic features of malignancy