Cytokinse Flashcards

1
Q

Which cell produce IL1

A

Macrophage

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2
Q

Which cell produce IL2

A

T-cell

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3
Q

Which cell produce IL3

A

T-cell

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4
Q

Which cell produce IL4

A

Th2

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5
Q

Which cell produce IL5

A

Th2

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6
Q

Which cell produce IL6

A

Macrophage

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7
Q

Which cell produce IL8

A

Macrophage

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8
Q

Which cell produce IL10

A

Th2

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9
Q

Which cell produce IL12

A

Macrophage

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10
Q

IL1 also called

A

Osteoclast activating factor

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11
Q

⬆️ IL1 lead to

A
  1. Fever
  2. Osteoporosis
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12
Q

IL2 function

A

Autocrine : exit from t-cell and stimulate the T-cell to proliferation

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13
Q

IL3 function

A
  1. Stimulate the proliferation of myeloid cell origin
  2. Stimulate the proliferation of granulocytes
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14
Q

IL4 function

A
  1. Convert IgM to IgE
  2. ⬆️ IgG
  3. ⬆️ Th2
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15
Q

IL5 function

A
  1. Convert IgM to IgA
  2. Increase eosinophils proliferation in bone marrow
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16
Q

IL6 function

A
  1. Acute phase reactant
  2. Produce fever
17
Q

Inducer of phagocytosis

A
  1. IgG
  2. C3b
  3. CRP
  4. IL8
18
Q

Which cell produce IL10

A

Th2

19
Q

IL10 function

A

Inhibit immune system

20
Q

IL11 function

A

⬆️ platelets

21
Q

Function of IL7

A

Convert the steam cell CD34 to lymphoid cell

22
Q

Activation of NK by

A
  1. IFN- alpha
  2. IFN-Beta
23
Q

NK cell activate the

A

IFN-gamma

24
Q

In case of transplant organ which IL most inhibit

A

IL-2, because Th1 activate CD8 that attack the graft by IL2

25
Q

In case of tumor, which IL most increase it

A

IL2 because the Th1 activate the CD8 that attack the tumor by IL2