Cytokines and Chemokines Flashcards
1
Q
Which monoclonal antibodies target TNFalpha?
A
infliximab, centolizumab, adalimumab, golimumab
2
Q
Which drug targets the TNF receptor fused to the Fc portion of IgG?
A
etanercept
3
Q
Which monoclonal antibody targets the IL-6Ra?
A
tocilizumab
4
Q
Which drug targets IL-1?
A
anakinra (human recombinant of IL-1RA)
5
Q
Which drug targets IL-2?
A
basiliximab
6
Q
What is basiliximab used for?
A
prophylaxis for renal transplant rejection
7
Q
Which monoclonal antibodies target IL-12/IL-23?
A
ustekinumab and briakinumab
8
Q
Which monoclonal antibody targets IL-17?
A
secukinumab
