cytokines and cds

Question 1

IL-1

Answer 1

pro-inflammatory

pyrogen

Question 2

IL-2

Answer 2

promote T cell growth

autocrine action

Question 3

IL-4

Answer 3

promote B cell growth
promote class switching IgE and IgG
promote differentiation of Th2
inhibit differentiation Th1

Question 4

IL-5

Answer 4

differentiation eosinophils
class switch IgA

Question 5

IL-6

Answer 5

pro-inflammatory like IL-1

Question 6

IL-8

Answer 6

recruit neutrophils

Question 7

IL-10

Answer 7

anti-inflammatory

Question 8

IL-12

Answer 8

T cell growth factor

promote Th1 subset

Question 9

IL-13

Answer 9

activate eosinophils

Question 10

IL-17

Answer 10

produced by Th17 T cell

promote neutrophil inflammation

Question 11

INF-y

Answer 11

promote macrophage phagocytosis
increase MHC expression
promote Th1
inhibit Th2

Question 12

TNF-a

Answer 12

pro-inflammatory

Question 13

TGF-b

Answer 13

anti-inflammatory

Question 14

CD3

Answer 14

T cell

Question 15

CD4

Answer 15

helper T cell

Question 16

CD8

Answer 16

cytotoxic T cell

Question 17

CD19

Answer 17

B cell

main identifier

Question 18

CD20

Answer 18

B cell

target for immunotherapy

Question 19

CD28

Answer 19

T cell costimulator

bind to CD80/86 on APC

Question 20

CTLA-4

Answer 20

molecule binds to CD80/86 better than CD28

Question 21

CD40

Answer 21

on B cell and APC

binds to CD40L to activate

Question 22

CD40L

Answer 22

on T cell

binds to CD40 to deliver signal

Question 23

CD56

Answer 23

NK cells

Question 24

CD38/138

Answer 24

plasma cells