Cytokines Flashcards
1
Q
Role of IL-2?
A
monocyte activation
2
Q
IL-2 is produced by…
A
Th1 cells and NK cells
3
Q
Role of IL-4?
A
Isotype switching to IgE
4
Q
Role of IL-8? What cell produces it?
A
Activation and chemotaxis of neutrophils.
Produced by Macrophages.
5
Q
Role of IL-10? Produced by what cells?
A
Anti-inflammatory: inhibits antigen presentation and cytokine production.
Produced by Th2 cells
6
Q
Function of INF-gamma? Produced by ?
A
-Activates monocytes -> macrophages
Made by NK cells and Th1 cells
7
Q
Function of TNF-alpha? Made by?
A
Fever, Acute phase response
Macrophages