Cystitis/Pyelonephritis Abx TBMD

Question 1

Ciprofloxacin

Answer 1

Fluoroquinolone

-Gram Neg: PSA, strep pneumoniae

Question 2

Levofloxacin

Answer 2

Fluoroquinolone

-Gran Neg: PSA, strep penumoniae

Question 3

Penicilin

Answer 3

-first line treatment for GAS (group A strep)

Question 4

Cephalosporin

Answer 4

• 4 generations

- as go up in generations: decrease in gram positive and increase in gram negative coverage

Question 5

Cefepime

Answer 5

• 4th gen cephalosporin
• GN: covers PSA
• less GP: covers MSSA and strep

Question 6

Carbapenem

Answer 6

• resistant to lactamases => use against ESBL producing strains
• GP cocci including MSSA
• GNR including PSA
• ESBL GNR
• Acinetobacter

Question 7

Ampicillin

Answer 7

• in cystitis/pyelonephritis use for enteroccus infxn

- covers MSSA and E. coli

Question 8

Nitrofurantoin

Answer 8

• 1st line abx for acute uncomplicated cystitis

- Doesn’t achieve adequate renal tissue levels => don’t use in pyelonephritis

Question 9

TMP-SMX

Answer 9

= Trimethorpim-Sulfamethoxazole

• first line abx for acute uncomplicated cystitis
• very effective if susceptible (20% of E. coli are resistant)
• Cover GNR except PSA

Question 10

Gentamicin

Answer 10

= Aminoglycoside

-GNR: including PSA

Question 11

1st Generation Cephalosporin

Answer 11

MSSA, GAS, E. coli, Klebsiella

Question 12

3rd Generation Cephalosporin

Answer 12

Strep, MSSA

-GN: H flu, E. coli, klebsiella, some for pseudomonas

Question 13

Vancoymycin

Answer 13

-G (+) including MRSA

Question 14

Macrolides (ex: Azithromycin)

Answer 14

Community acquired pneumonia

Question 15

Daptomycin

Answer 15

-all resistant gram (+) including MRSA, VRE, VISA

Question 16

Linezolid

Answer 16

= Oxazolidinone

-all resistant gram (+): MRSA, VRE, VISA

Question 17

Ceftriaxone

Answer 17

= 3rd gen cephalosporin

• Strep, MSSA
• GN: H. flu, E. coli (not PSA)

Question 18

Cephazolin

Answer 18

= First gen cephalosporin

-MSSA, GAS, E. coli, proteus sp, klebsiella