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Neuro drug > CYPs > Flashcards

CYPs Flashcards

1
Q

CYP1A2

Substrate
Inducer
Inhibitors

A

Inducer

Rifampicin
Phenobarbitone
Phenytoin
Cigarette smoking

Inhibitor
Fluoxamine 
Ciprofloxacin 
Ketoconazole 
Isoniazid 
Quinolone
Macrolide
Substrate 
Phenothiazine
Halo
Cloz 
Olan
Zip

Warfarin
Theophylline
Agomelatin
Amiodarone

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2
Q

CYP2D6

Substrate
Inducer
Inhibitor

A

Inducer

Rifampicin
Phenobarbitone
Phenytoin
Carbamazepine

Inhibitor
Fluoxamine 
Paroxetine
Bupropion
Duloxetine 
Substrate
Phenothiazine
Halo 
Olan
Ari
Ris
Zuclopenthixol 
Metoprolol 
Codeine
Oxycodeine
Hydrocodone 
Tramadol

Despiramine

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3
Q

CYP3A4

Substrate
Inducer
Inhibitor

A

Inducer

Barbiturates
Phenytoin
Carbamazepine

Inhibitor

Fluoxamine 
Isoniazid 
Norfluoxetine
TCAs
Imidazole 
Macrolide

Cipro
Cimetidine

Substrate 
Quet 
Zip
Ari
Risp

Simvastatin
Lovastatin

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4
Q

CYP2C19

Substrate
Inhibitor

A

Substrate

Warfarin

Inhibitor
Fluoxamine
Fluoxetine
Moclobemide

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5
Q

CYP2C9

Substrate

A

Tolbutamide
Warfarin
Phenytoin

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6
Q

Warfarin CYP

A

1A2
2C9
2C19

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7
Q

Phenytoin CYP

A

2C9. S

Inducer
1A2
2D6
3A4

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Neuro drug (21 decks)

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