CYP3A4 Inducers, Inhibitors, and Substrates Flashcards

1
Q

topiramate

A

Inducer

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2
Q

erythromycin

A

Substrate and Inhibitor*

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3
Q

phenobarbital

A

Inducer

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4
Q

grapefruit

A

Inhibitor**

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5
Q

prednisone

A

Inducer

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6
Q

phenytoin

A

Inducer

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7
Q

ziprasidone

A

Substrate

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8
Q

ranolazine

A

Substrate and Inhibitor

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9
Q

ketoconazole

A

Substrate and Inhibitor**

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10
Q

hydrocodone

A

Substrate

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11
Q

nifedipine

A

Substrate and Inhibitor

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12
Q

pioglitazone

A

Inducer

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13
Q

linagliptin

A

Substrate

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14
Q

carbamazepine

A

Substrate and Inducer

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15
Q

alprazolam

A

Substrate

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16
Q

dexamethasone

A

Substrate and Inducer

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17
Q

salmeterol

A

Substrate

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18
Q

aripiprazole

A

Substrate

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19
Q

tramadol

A

Substrate

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20
Q

amitriptyline

A

Substrate

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21
Q

lovastatin

A

Substrate

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22
Q

verapamil

A

Substrate and Inhibitor*

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23
Q

colchicine

A

Substrate

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24
Q

fluoxetine

A

Inhibitor

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25
fluvoxamine
Inhibitor
26
iloperidone
Substrate
27
cimetidine
Inhibitor
28
haloperidol
Substrate
29
amiodarone
Substrate and Inhibitor
30
venlafaxine
Substrate
31
felodipine
Substrate
32
voriconazole
Substrate and Inhibitor**
33
clozapine
Substrate
34
St. John’ s wort
Inducer
35
(R)-warfarin
Substrate
36
levonorgestrel
Substrate
37
buspirone
Substrate
38
modafinil
Inducer
39
methylprednisolone
Substrate
40
posaconazole
Inhibitor**
41
quetiapine
Substrate
42
repaglinide
Substrate
43
saxagliptin
Substrate
44
buprenorphine
Substrate
45
amlodipine
Substrate and Inhibitor
46
sertraline
Substrate
47
clarithromycin
Substrate and Inhibitor**
48
brexpiprazole
Substrate
49
citalopram
Substrate
50
isoniazid
Inhibitor
51
atorvastatin
Substrate
52
oral contraceptives
Substrate
53
fluconazole
Inhibitor*
54
Viekira Pak
Substrate
55
ritonavir
Substrate Inhibitor** and Inducer
56
trazodone
Substrate
57
eplerenone
Substrate
58
estrogens
Substrate
59
omeprazole
Substrate
60
etonogestrel
Substrate
61
diltiazem
Substrate and Inhibitor*
62
midazolam
Substrate
63
rifampin
Inducer
64
oxycodone
Substrate
65
fentanyl
Substrate
66
nefazodone
Substrate and Inhbitor**
67
dextromethorphan
Substrate
68
ciprofloxacin
Inhibitor*
69
itraconazole
Substrate and Inhibitor**
70
dronedarone
Inhibitor*
71
ethinyl estradiol
Substrate and Inhibitor
72
diazepam
Substrate
73
oxcarbazepine
Inducer
74
simvastatin
Substrate
75
lomitapide
Substrate
76
telithromycin
Substrate and Inhibitor**
77
esomeprazole
Substrate
78
triazolam
Substrate
79
lurasidone
Substrate
80
rivaroxaban
Substrate