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PHRM 5501 Pharmacokinetics > CYP3A4 Inducers, Inhibitors, and Substrates > Flashcards

CYP3A4 Inducers, Inhibitors, and Substrates Flashcards

1
Q

topiramate

A

Inducer

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2
Q

erythromycin

A

Substrate and Inhibitor*

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3
Q

phenobarbital

A

Inducer

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4
Q

grapefruit

A

Inhibitor**

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5
Q

prednisone

A

Inducer

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6
Q

phenytoin

A

Inducer

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7
Q

ziprasidone

A

Substrate

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8
Q

ranolazine

A

Substrate and Inhibitor

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9
Q

ketoconazole

A

Substrate and Inhibitor**

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10
Q

hydrocodone

A

Substrate

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11
Q

nifedipine

A

Substrate and Inhibitor

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12
Q

pioglitazone

A

Inducer

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13
Q

linagliptin

A

Substrate

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14
Q

carbamazepine

A

Substrate and Inducer

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15
Q

alprazolam

A

Substrate

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16
Q

dexamethasone

A

Substrate and Inducer

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17
Q

salmeterol

A

Substrate

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18
Q

aripiprazole

A

Substrate

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19
Q

tramadol

A

Substrate

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20
Q

amitriptyline

A

Substrate

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21
Q

lovastatin

A

Substrate

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22
Q

verapamil

A

Substrate and Inhibitor*

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23
Q

colchicine

A

Substrate

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24
Q

fluoxetine

A

Inhibitor

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25
Q

fluvoxamine

A

Inhibitor

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26
Q

iloperidone

A

Substrate

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27
Q

cimetidine

A

Inhibitor

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28
Q

haloperidol

A

Substrate

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29
Q

amiodarone

A

Substrate and Inhibitor

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30
Q

venlafaxine

A

Substrate

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31
Q

felodipine

A

Substrate

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32
Q

voriconazole

A

Substrate and Inhibitor**

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33
Q

clozapine

A

Substrate

34
Q

St. John’ s wort

A

Inducer

35
Q

(R)-warfarin

A

Substrate

36
Q

levonorgestrel

A

Substrate

37
Q

buspirone

A

Substrate

38
Q

modafinil

A

Inducer

39
Q

methylprednisolone

A

Substrate

40
Q

posaconazole

A

Inhibitor**

41
Q

quetiapine

A

Substrate

42
Q

repaglinide

A

Substrate

43
Q

saxagliptin

A

Substrate

44
Q

buprenorphine

A

Substrate

45
Q

amlodipine

A

Substrate and Inhibitor

46
Q

sertraline

A

Substrate

47
Q

clarithromycin

A

Substrate and Inhibitor**

48
Q

brexpiprazole

A

Substrate

49
Q

citalopram

A

Substrate

50
Q

isoniazid

A

Inhibitor

51
Q

atorvastatin

A

Substrate

52
Q

oral contraceptives

A

Substrate

53
Q

fluconazole

A

Inhibitor*

54
Q

Viekira Pak

A

Substrate

55
Q

ritonavir

A

Substrate Inhibitor** and Inducer

56
Q

trazodone

A

Substrate

57
Q

eplerenone

A

Substrate

58
Q

estrogens

A

Substrate

59
Q

omeprazole

A

Substrate

60
Q

etonogestrel

A

Substrate

61
Q

diltiazem

A

Substrate and Inhibitor*

62
Q

midazolam

A

Substrate

63
Q

rifampin

A

Inducer

64
Q

oxycodone

A

Substrate

65
Q

fentanyl

A

Substrate

66
Q

nefazodone

A

Substrate and Inhbitor**

67
Q

dextromethorphan

A

Substrate

68
Q

ciprofloxacin

A

Inhibitor*

69
Q

itraconazole

A

Substrate and Inhibitor**

70
Q

dronedarone

A

Inhibitor*

71
Q

ethinyl estradiol

A

Substrate and Inhibitor

72
Q

diazepam

A

Substrate

73
Q

oxcarbazepine

A

Inducer

74
Q

simvastatin

A

Substrate

75
Q

lomitapide

A

Substrate

76
Q

telithromycin

A

Substrate and Inhibitor**

77
Q

esomeprazole

A

Substrate

78
Q

triazolam

A

Substrate

79
Q

lurasidone

A

Substrate

80
Q

rivaroxaban

A

Substrate

PHRM 5501 Pharmacokinetics (6 decks)

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