CYP3A4 Flashcards
1
Q
CYP3A4 substrate
A
cyclosporine, FK506 corticosteroids erythromycin felodipine, isradipine nifedipine, nisoldipine nitrendipine digoxin, quinidine verapamil warfarin sildenafil astemizole terfenadine pioglitazone
2
Q
CYP3A4 inhibitors
A
erythromycin clarithromycin diltiazem ketoconazole fluconazole itraraconazole quinidine grapefruit juice cimetidine indinavir fluoxetine zileuton, zafirlukast verapamil amiodarone
3
Q
CYP3A4 Inducers
A
Carbamazipine phenobarbital rifanpin rifabutin phenytoin corticosteroids troglitazone St. John's wort
