Cyp interactions Flashcards

1
Q

1A2

A
Inhibitors = Abx (erythromycin, ciprofloxacin)
Substrates = clozapine, olanzepine
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2
Q

2C9

A

Inhibitors: FluConazole
Substrate: Warfarin, Phenytoin, (NSAIDs)

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3
Q

2C19

A

Inhibitors: PPI, Isoniazid
- Note will decrease effect of Clopidogrel as prodrug
Substrate: Clopidogrel **
Diazepam

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4
Q

2D6

A

Inhibitors: Depression - SSRIs
Substrates: coDeine , D= Tamoxifen*, Metoprolol

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5
Q

3A4

A

ABx - fungals (azole), macrolides (erythomycin), HIV - ritonavir
Substrate: CNI, amiodarone, verapamil, midazolam, statins, sildafenil, oesetrogens

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6
Q

Always inducing (decrease effect of substrate unless prodrug)

A

CBZ
Phenytoin
Rifampicin
(St Johns Wort)

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