CVS Flashcards
What factors effect diffusion?
- AREA - capillary density
- CONCENTRATION GRADIENT- rate of blood flow must be high enough to maintain the gradient. A greater gradient causes a faster rate of diffusion
- RESISTANCE - the nature of the barrier, the nature of the molecule & the DISTANCE needed to be travelled
What is the blood flow into the gut (incl. liver) at rest and peak?
1.4L/min @ rest & 2.4L/min peak
What is the blood flow to the brain
750ML/MIN
what is the blood flow to the kidney
1.2L/min
What is the blood flow to the muscles: at rest & at peak?
1L –> 16L/min
What is the formula for cardiac output
CO = stroke volume x heart rate
What is the stroke volume?
The volume of blood pumped out of the heart per cycle. =
EDV-ESV
what are capacitance vessels? What are the main capacitance vessels & what is their function
They have the ability to store blood by distension.
Veins
React to changes in cardiac output
What are the resistance vessels?
Arterioles & pre-capillary sphincters
What is the distribution of the blood in the vessels? i.e. what percentage in each type of vessel/organ?
Veins 67%
Heart & Lungs 17%
Arteries 11%
Capillaries 5%
What is the anatomical location of the heart?
In the middle mediastinum, within the pericardium. Superior to the diaphragm & deep to the sternal angle
How is the mediastinum divided?
Into superior & inferior by the sternal angle.
Within the inferior mediastinum is the anterior, middle and posterior mediastinum.
What is inside the middle mediastinum?
The heart, the pericardium and the great vessels
What is the structure of the pericardium?
The pericardium is a FIBROSEROUS SAC
Three layers:
FIBROUS OUTER LAYER
PARIETAL SEROUS LAYER
VISCERAL SEROUS LAYER
The pericardial space between the parietal and visceral layers has a thin film of fluid for FRICTIONLESS BEATING
How is the cardiothoracic ratio calculated? What is it indicative of?
Used to determine if CARDIOMEGALY/ PERICARDIAL EFFUSION is present.
Measure along the base of the lungs between the lateral extremities of the ribs (width of thoracic cavity).
Measure the width of the heart.
Heart should normally be