CVS Flashcards
For patients with mildly elevated triglycerides of <4mm what treatment can you consider?
standard statins
for moderatley elevated triglycerides >4mmol what therapy can you initiate?
fenofibrate, reducing dose with decreasing eGFR
145mg OD (eGFR >60)
96mg (eGFR 20-60)
48mg (eGFR 10-20)
Secondary prevention of cardiovascular events includes what medications?
Lipid lowering medications regardless of lipid levels - use high intensity statin.
Antiplatelet agent
ACEI - titrated to max dose tolerated
After an ACS event what antiplatelet therapy should be initaiated for seocndary prevention?
Aspirin 100-150mg OD PLUS clopidogrel 75mg OD (or alt) for 12 months, then cease the P2Y12 inhibitor
Dores intermittent claudication require DAPT?
NO. Single agent (eTG)
After an ACS event your patient is commenced on DAPT, a statin, an ACEI and what else?
Betablocker unless they have decompensated HF, heart block or bradycardia.
Options include:
Atenolol 25-100mg
metoprolol 25-100mg.
Post ACS your patient has an EF of <40%, what are the prefered beta blockers in this instance?
bisoprolol 1.25mg OD
carvedilol (weight based dosing)
nebivolol 1.25mg
metoprolol succinate MR 23.75mg OD
start very low go very slow
Aldosterone antagonists (MRA) improve survival time and reduce hospitalisations if patient with HFrEF.
Which drugs and dosings do you commence?
spironolactone 25mg OD increasing to 50mg if needed
OE
eplerenone 25mg OD increasing to 50mg if needed
You commence spiro for a patient with HFrEF, what can you expect to see on bloods?
A small rise (within normal limits) of potassium.
In those with CKD adding spiro when on an ACE can cause severe hyperkalaemia
Anticoags in AF with no inc bleeding risk?
apixaban 5mg BD
Anticoags AF with inc bleeding risk (>80, weight <60, creatinine >133 micromol/L)
apixaban 2.5mg BD
Anticogs AF with creat cl <30?
CrCl >50nrivaroxaban 20mg OD
if CrCl 15-49 15mg OD
RAte cntrol in AF?
Aim <110 bpm
atenolol 25mg OD
metoprolol 25mg OD
Rate control in AF when LV dysfunction?
diltiazem or verapamil MR 180mg
grade 1 mild HTN
104-159 / 90-99