CV system and its anatomy Flashcards
what is a CV system used for?
transport of O2, of CO2, of hormones and of heat
varies with tissues needs
What can peripheral vascular disease cause?
it is a peripheral artery disease and due to vasospasm and atherosclerosis inflammation
causes ischaemia
how does CVD prevalence change with age?
as you get older you have a higher prevalence of CVD
what does cardiac output depend on and how can you figure it out?
depends on
- heart rate
- stroke volume; volume pumped per beat
CO = HR x SV
what does it mean by systole and diastole?
systole is the pumping phase of the heart
-> muscle expands
diastole is the relaxing part of the cycle
-> muscle recoils
how would systolic and diastolic pressure be seen on a graph and what does this show?
systolic is the peak of the curve and diastolic is the trough
at diastolic this is when the blood is pumped out
there is a pressure gradient from arteries (ABP) to veins (CVP)
what is the relationship between cardiac output and venous return?
venous return = cardiac output
- if this is not true the system is out of balance
what does the mean ABP depend on?
- volume of blood pumped out per min
- resistance of circulation
how can you calculate the systemic and pulmonary mean ABP? how do you calculate the TPR using PVR
systemic mean ABP = TPR x CO
-> should be around 90mmHg (narrower vessels so higher pressure)
pulmonary mean ABP = PVR x CO
-> should be around 12-15 mmHg
to find TPR = 7 x PVR
what can constriction arterioles cause?
this causes the ABP to increase as ABP = CO x TPR and as arterioles constrict the TPR increases so ABP increases also
what happens when arterioles in the tissue constrict? and what occurs when they dilate?
when tissue arterioles constrict, the local resistance increases and so the total blood flow will decrease; causing pressure in capillaries to decrease
when they dilate, the local resistance decreases, total blood flow increase and capillary pressure increases
what are the types of vessels and their elastic functions?
- elastic arteries; for strength and have elastic recoil
- muscular arteries; for distribution
- capillaries; for exchange of nutrients, gases etc.
- arterioles; have varying resistance to affect ABP and the total blood flow
what is the role of venues/veins?
- determine filling of ventricles
- venues increase vein pressure causing pressure in capillary to increase => oedema
- has a reservoir function
what are the functional parts of the CVS?
- conducting part ; arteries and veins
- exchange part ; capillary bed
what is the structure of the vessel wall?
- tunica externa; collagen
- tunica media ; thick smooth muscle
- > thickest layer - tunica intima ; endothelium
- > can have valves
why does arterioles have elastic tissue?
need it to expand and recoil due to the high blood pressure in the arterioles
what is capillary beds made up of?
endothelial cell layer
-> one cell thick wall; allows diffusion to cells though the extracellular space