CV pharmacology Flashcards
Antiplatelet agents
ASA, thienopyridines, diperidamole, 2b3a antagonists, dextran
thienopyridines
(AKA P2Y12 inhibitors) clopidogrel, prasugrel, ticlopidine, ticagrelor
2b3a antagonists
abciximab, eptifibatide, tirofiban
which of the p2y12 inhibitors is reversible? which is not a prodrug?
ticagrelor, ticagrelor
common fibrinolytics
streptokinase, alteplase (tPA), tenecteplase (TNK-tPA)
coronary blood flow gradient
LVEDP, Ao diastolic pressure
anti anginal drugs
beta blockers, CCB’s, nitrates
do beta blockers primarily affect arteries or veins
arteries
by what mechanism do nitrates work
formation of Nitric oxide, conversion of GTP to cyclic GMP which induces relaxation
what is a difference b/w dihydropyridine and non-dihydropyridine
dihydros increase HR while non-dihydros decrease HR.
do CCB’s work more on arterial or venous side
arterial
what are some dihydro ccb’s
“-ipine” amlodipide, felodipine
what are some non-dihydro ccb’s
diltiazem, verpamil
side effects of beta blockers
asthma, bradycardia, AV conduction problems, fatigue, sexual disfxn, peripheral vascular disease, sick sinus syndrome
side effects of nitrates
headaches, hypotension, syncope, bradycardia, aortic stenosis, tolerance