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CV2 > CV pharmacology > Flashcards

CV pharmacology Flashcards

1
Q

Antiplatelet agents

A

ASA, thienopyridines, diperidamole, 2b3a antagonists, dextran

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2
Q

thienopyridines

A

(AKA P2Y12 inhibitors) clopidogrel, prasugrel, ticlopidine, ticagrelor

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3
Q

2b3a antagonists

A

abciximab, eptifibatide, tirofiban

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4
Q

which of the p2y12 inhibitors is reversible? which is not a prodrug?

A

ticagrelor, ticagrelor

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5
Q

common fibrinolytics

A

streptokinase, alteplase (tPA), tenecteplase (TNK-tPA)

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6
Q

coronary blood flow gradient

A

LVEDP, Ao diastolic pressure

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7
Q

anti anginal drugs

A

beta blockers, CCB’s, nitrates

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8
Q

do beta blockers primarily affect arteries or veins

A

arteries

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9
Q

by what mechanism do nitrates work

A

formation of Nitric oxide, conversion of GTP to cyclic GMP which induces relaxation

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10
Q

what is a difference b/w dihydropyridine and non-dihydropyridine

A

dihydros increase HR while non-dihydros decrease HR.

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11
Q

do CCB’s work more on arterial or venous side

A

arterial

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12
Q

what are some dihydro ccb’s

A

“-ipine” amlodipide, felodipine

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13
Q

what are some non-dihydro ccb’s

A

diltiazem, verpamil

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14
Q

side effects of beta blockers

A

asthma, bradycardia, AV conduction problems, fatigue, sexual disfxn, peripheral vascular disease, sick sinus syndrome

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15
Q

side effects of nitrates

A

headaches, hypotension, syncope, bradycardia, aortic stenosis, tolerance

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16
Q

side effects of calcium antagonists

A

bradycardia, heart failure, LV disfxn, peripheral edema, sick sinus syndrome, dizziness, hypotension, flushing

17
Q

mechanism of ranolizine

A

late Na+ current inhibitor.

18
Q

role of Ang II in organ failure

A

htn, atherosclerosis, heart failure, nephropathy

19
Q

what receptors does Ang II deleteriously bind to

A

AT1

20
Q

common ACEI

A

“-pril” captopril, enalapril

21
Q

common side effects of ACEI

A

cough, skin reactions, angioedema, renal disfunction

22
Q

common ARB’s

A

“-sartan” losartan, valsartan

23
Q

what effect do beta blockers have on coronary artery perfusion

A

none

CV2 (16 decks)

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