CV (class 3-end) Flashcards
________ _____ ______ is characterized by damage to or a defect in one of the four heart valves: the mitral, aortic, tricuspid or pulmonary.
Valvular heart disease
________ _______: the inability of one of the heart’s valves to open properly, resulting in a reduced volume of blood exiting the chamber and considerable pressure in the exit chamber.
Valvular stenosis
_________ _______: An autoimmune reaction secondary to infection by streptococcus bacteria. After a period of some weeks, antibodies which have developed to fight the infection appear to sense a chemical similarity between the bacteria and heart tissue.
Rheumatic Fever
Mention of heart murmur or any of the causes of valvular disorder on the case history should lead to the RMT establishing _____ _________ with patient.
CCHF Status
T/F: All heart murmurs are clinically significant.
False
______ _____ heart murmurs typically indicate some degree of heart failure
Adult onset
T/F: When treating a patient with a heart murmur, you can probably expect to see a decrease in BP post-treatment.
False: There will probably be an increase.
The most common cause of mitral valve prolapse (MVP) is abnormally stretchy or “floppy” valve leaflets (called _____________ valve disease) and their supporting chordae tendonae, causing parts of the valve flop or bulge back into the atrium.
Myxomatous valve disease
T/F: Mitral Valve Prolapse doesn’t always cause backflow/ regurgitation. In fact, most people who have MVP don’t have backflow and never have any related symptoms or problems.
True
With MVP, a ‘click’ sound can be heard during _______, which is the protrusion due to the valve damage and the leaking of blood back into the upper chambers.
Systole
T/F: Mitral valve prolapse occurs in about 15% of the population.
False: 5%
A genetic connective tissue disorder, specifically it affects the elastic fibers in the extracellular matrix. Patients present with long and thin body with long fingers - “spider hands”, joint hypermobility, spinal deformities - pectus excavatum or pigeon chest. Eyes may also feature bilateral dislocation of the lens, due to weakness of the suspensory ligaments, myopia (near sightedness), retinal detachment.
Marfan’s Syndrome
What effect does Marfan’s Syndrome have on a patient’s CV system?
They are prone to mitral valve prolapse, progressive dilation of the aortic valve ring, weakness of the aorta or other arteries.
Expected life expectancy is 30-40 years old, surgery and medications prolong life, echocardiogram every 6 months to monitor the status of the aorta, canes and wheelchairs are a possibility.
Defined as an increase in the amount of fluid in the interstitial space either beneath the skin or in an organ cavity, typically palpable. It can be a local or generalized condition.
Edema
________: excess fluid in the peritoneal cavity
Ascites
_______: Edema, usually of the skin of the extremity, that, when firmly pressed with a finger, will maintain the depression produced by the finger.
Pitted Edema
_________ ____s are a symptom of chronic venous insufficiency in the superficial veins.
Varicose veins
Blood Pressure = _____ _____ x _____ _______ x _____ __________ __________
Blood Pressure = Heart Rate x Stroke Volume x Total Peripheral Resistance
or
Blood Pressure = Cardiac Output x Total Peripheral Resistance
Abnormal drop in blood pressure with a change in position, usually moving from a recumbent to a standing position.
Orthostatic/Postural Hypotension
_________ _________: the inability of the patient to stand upright for 1-2 minutes. Other symptoms include: dizziness, visual changes, head and neck discomfort, poor concentration, palpitations, tremor, anxiety, syncope.
Orthostatic Intolerance
The result of a decrease in blood pressure right after eating a meal.
Postprandial Hypotension
For a person with diabetes, a threshold of ≥ ___/__ is used to determine hypertension, regardless of measurement method.
130/80
____% of hypertensive population have Primary/Benign/Essential/Idiopathic Hypertension
90-95%
Situations where the blood pressure elevates, sometimes quite dramatically, when readings are being taken by medical professionals. The person may otherwise have normal pressure or significantly lower readings.
White Coat Hypertension
___-_______ _________: aka “bad cholesterol” transports cholesterol particles throughout the body. LDL cholesterol builds up in the walls of arteries, making them hard and narrow.
Low-density Lipoproteins
High-density lipoproteins (HDL), or “good” cholesterol, picks up excess cholesterol and takes it back to the ____.
Liver
Addition of more squamous epithelial
cells/layers to reinforce the tissue, a clear, thick, goopy, inflexible material that looks like hyaline, can described as “heavy marshmallow”
Hyalinization
Inner endothelial wall of blood vessel (tunica
intima/Interna) becomes damaged and repairs with scar tissue due to the force of the blood pressure.
Onion Skinning
T/F: Massage Therapy decreases blood viscosity.
True: Increased fluid return from tissue can increase blood plasma volume, lowering red blood cell concentration, causing hemodilution
As a massage progresses, ____________ the sympathetic tone and total peripheral resistance tends to outweigh the _______ venous return (cardiac output) and the net end effect is usually a slight ________ in blood pressure from the original (pre-massage) reading.
As the massage progresses, decreasing the sympathetic tone and total peripheral resistance tends to outweigh the increased venous return (cardiac output) and the net end effect is usually a slight decrease in blood pressure from the original (pre-massage) reading.
The increased cardiac output of massage can result in an overall increase of blood pressure, which peaks in the first ___ minutes and is somewhat mitigated by activation by the parasympathetic nervous system by the end of treatment.
15 minutes
Type of medications that acts on kidneys (nephrons) to increase production of urine / decrease blood volume and therefore hydrostatic pressure.
Diuretics/Water Pills
____ ________s modify sympathetic nervous system reactivity by competing with sympathetic neurotransmitters (adrenaline, norepinephrine) for the beta receptor sites of the heart.
Beta Blockers
__________s slow down the heart rate and increase the efficiency of contraction (which increases the force of contraction) and refilling phases of the cardiac cycle, causing similar results to beta blockers.
Glycosides
______ _______s either block sympathetic neurotransmitters (catecholamines, such as norepinephrine-NE) from synapsing on the smooth muscle of the arterial system or decrease the number of sympathetic neurotransmitter impulses emitted from the vasomotor center in the brain.
Alpha Blockers
_______ __________ modify/limit the uptake and use of
calcium in smooth muscle cells in blood vessel walls (in the tunica media layer), and some also work in the cardiac muscle (in the AV node), thereby decreasing the tone of the smooth muscle in the blood vessel walls and improving the contractile properties of cardiac muscle.
Calcium Antagonists / Calcium Channel Blockers
If you ______ ACE (Angiotensin Converting Enzyme), you ____ the amount of Angiotensin II and _____ vasoconstriction.
If you inhibit ACE (Angiotensin Converting Enzyme), you limit the amount of Angiotensin II and reduce vasoconstriction.
_____ (an enzyme) is produced in the kidneys and released into circulation when blood pressure decreases to initiate the renin-angiotensin system.
Renin
___________s slow down clotting, thereby reducing fibrin formation and preventing clots from forming and growing.
Anticoagulants
Drugs called __________ actively break down thrombi and clots, typically used in hospital settings, in urgent or emergency situations.
Thrombolytics
\_\_\_\_\_\_\_ \_\_\_\_\_\_\_\_ is the normal condition for blood flow throughout most of the circulatory system. It is characterized by concentric layers of blood moving in parallel down the length of a blood vessel. The highest velocity is found in the center of the vessel. The lowest velocity is found along the vessel wall.
Laminer Flow
The highest velocity of blood flow is found in the center of the _____. The lowest velocity is found along the vessel ____.
The highest velocity is found in the center of the vessel. The lowest velocity is found along the vessel wall.
The highest velocity of blood flow is found in the center of the _____. The lowest velocity is found along the vessel ____.
The highest velocity is found in the center of the vessel. The lowest velocity is found along the vessel wall.
Under conditions of high blood flow - such as from high blood pressure - particularly in the ascending aorta, laminar flow can be disrupted and become ________.
Turbulent
Turbulence increases the energy required to drive blood flow because it increases the loss of energy in the form of friction, which generates ____.
Heat
The formation or presence of a blood clot in a blood vessel, i.e.vein or artery is called _________. The clot itself is called a _______.
Thrombosis
Thrombus
With atherosclerosis, fatty deposits called ______s build up between the tunica intima and tunica media walls of the arteries and cause them to harden and narrow
Plaques
________ are recruited to the injured blood vessel to form an initial plug.
Platelets
_______ is a protein that crosslinks with itself to form a mesh that makes up the final blood clot.
Fibrin
If occlusion occurs in coronary artery, it can cause a _______ ________/heart attack.
Myocardial infarction
Blood clots in a vein (______ ________) can occur when a person becomes immobilized and muscles are not contracting to push blood back to the heart
Venous thrombosis