CV Flashcards

1
Q

pHTN Definition

A

Normal pulm pressures 25/10, mean 15

Mean > 25 at rest

Mean > 30 while exercising

HTN Crisis - Near systemic or suprasystemic with sever right heart failure

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2
Q

pHTN Classification

A
  1. Pulmonary artery htn
  2. PHTN with left heart failure
  3. PHTN with lung disease and hypoxemia
  4. PHTN secondary to chronic thrombotic events or embolic disease
  5. Misc
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3
Q

R=delta P/ flow

A
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4
Q

How do you treat pHTN Crisis?

A
  1. 100% FiO2
  2. Alkalosis
    • Bicarb
    • Hyperventilate (decrease PaCO2)
  3. Decreased PVR
    • FRC, lung volumes
    • Sedation
  4. Support RV (support LV, preload)
  5. Avoid pulm vasoconstrictors
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5
Q
A
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6
Q

Single Ventricle

Description?

Goal?

A
  • Aortic and pulm artery saturations are approximately equal
  • Goal -> achieve balance between puml and systemic circulations
  • Qp=Qs
  • Qp=CO to pulm circulation
  • Qs=CO to systemic circulation
  • Total CO shared between pulm and systemic circulations
  • Qp:Qs determined by SVR and PVR
  • High Qp:Qs low systemic O2 delivery
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7
Q

Single Ventricle Management

A
  • Optimize DO2 without increase in SaO2
  • Goal Qp:Qs 0.5-1
  • Increase CO = increase DO2

Ex Qp:Qs 2:1 -> pumping 3 COs

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8
Q

Resistance to Pulm BF

A
  • Valvular and subvalvular PS
  • Pum arteriolar R (PVR)
  • Pulm venous and LA Pressure
  • AV valve restrictions
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9
Q

Resistance to Systemic BF

A
  • Presence of anatomic obstructive lesions:
    • Aortic stenosis
    • Arch hypoplasia/ Coarc
    • Subaortic obstruction
  • SVR
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10
Q

How to increase Qs?

A
  • Reduce SVR
    • sedation - decrease sympathetic output
    • nipride - venous and arteriolar vasodilation
    • milrinone
    • alpha blockers
  • Increase DO2 via increase CO
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11
Q

How to decrease Qp?

A
  • Increase PVR
    • PEEP -> increased lung volumes –> increase PVR
    • Increase pCO2 -> hypovent, bleed 2-5% CO2
    • Decrease pH-> acidosis
    • Decrease fiO2
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12
Q

pHTN Pathophysiology

A
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13
Q
A
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