Cutaneous Wound Healing Flashcards
how thick is skin?
1.4 to 4 mm
epidermis is vascular or avascular?
avascular
what kind of tissue is the dermis?
loose connective tissue
hyperkeratosis is a thickening of what stratum layer of skin? Who usually has this?
stratum corneum - people with diabetes
what is maceration?
excess humidity of tissue - whitish skin (like when bandaid on too long)
eschar is what?
black crust from necrotic cutaneous or mucous covering
in partial thickness wounds, which cells are doing most of the healing work?
keratinocytes - reepithelialization from edges and areas around glands and hair follicles (epithelial buds)
in full-thickness wounds, what is the primary mechanism that healing uses? what kind of tissue is laid down?
wound contraction - scar tissue
what are the 4 stages of wound healing?
hemostasis
inflammatory
proliferation
remodelling
what type of environment is required for autogenic debridement?
humid
what three types of cells are involved in the proliferative stage?
fibroblasts
endo and epi thelial cells
when is a wound a chronic one?
4-12wks +
when it takes forever to heal and does not respond well to treatment
name four types of chronic wounds
pressure ulcers
venous ulcers
arterial ulcers
neuropathic ulcers
how long does one have to be immobile before pressure ulcers start?
only 1-2 hours
a stage one pressure sore is unbroken skin, but will do what when a persistently red area is pushed with a finger?
it will not whiten, it will remain red
stage two pressure ulcers involve loss of dermis or epidermis or both. What will this look like clinically?
looks like an abrasion, blister, or shallow crater, occasionally with fibrin and looking light red otherwise
Stage three goes down to the subcutaneous layer but not beyond underlying fascia. It will look like a deep crater. What else can be present?
sinus tracts and undermining. Necrotic tissue may also be present
stage four is all the way down and will have necrosis. what other structures might be affected?
muscle, bone, joint capsule
unspecified pressure sores may involve what?
eschar or humid necrotic tissue covering wound bed, so unable to tell stage of ulcer
does it hurt to push on pressure sores?
of course it is
with venous ulcers, venous distension leads to cells leaking out into tissues where they become brown and swollen. What is this browning called?
hemosiderin
what happens after the leaking and browning?
dermatosclerosis, and finally lipodermatosclerosis
venous hypertension can come from insufficient valves but also obstruction. What are two ways the veins may become obstructed?
obesity
pregnancy
thrombosis
what do venous ulcers usually look like?
shallow weirdly shaped on the bottom 1/3 of the legs. contains moderate exudate
may have swelling, hemosiderin, varicosities and white athrophies surrounding ulcer