Cutaneous T cell lymphoma(medscape) Flashcards

1
Q

Cutaneous T cell lymphoma is a type of

A

NHL

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2
Q

Distribution of patches in mycosis fungoides

A

bikini area

lower trunk and buttocks

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3
Q

Plaque phase of mycosis fungoides

A

intensly pruritic

Lymphadenopathy

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4
Q

Tumors in MF

A

prone to ulceration

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5
Q

Sezary syndrome,clinical presentation

A

edematous skin

lymphadenopathy

hepatosplenomegaly

palmoplantar hyperkeratosis

alopecia

nail dystrophy

ectropion

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6
Q

Minimum amount of sezary cells required for diagnosis

A

>1000 cells/µL

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7
Q

Immunophenotypic abnormalities in sezary syndrome

A

CD4/CD8 ratio of more than 10

Loss of any or all of T cell antigens CD2,CD3,CD4,CD5

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8
Q

Second most common extranodal site for lymphomas

A

Skin

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9
Q

primary cutaneous Cd30 positive lymphoproliferative disorders

A

Anaplastic large cell lymphoma cutaneous type(ALK negative)

lymphomatoid papulosis

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10
Q

Difference between cutaneous and systemic anaplastic large cell lymphoma

A

absence of t(2;5) in cutaneous form

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11
Q

Size of lymphomatoid papulosis

A

<2cm

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12
Q

20% of Lymphomatoid papulosis may evolve into

A

HD

Cutaneous anaplastic large cell lymphoma

MF

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13
Q

Cd of subcutaneous panniculitis like T cell lymphoma

A

CD8+ CD3+

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