Cutaneous Manifestations of Systemic Diseases

Question 1

Addisons

Answer 1

adrenal insuff. hyperpigmentation of palmar creases and mucosal surfaces

Question 2

Cushing’s

Answer 2

Buffalo Hump

Question 3

Rheumatoid Arthritis

Answer 3

red-brown macules on the legs

Question 4

Lichen Planus

Answer 4

Wickham’s striae, nail

Question 5

Fabry’s

Answer 5

alpha galactosidase A deficiency.

mulberry cells and maltese cross

Question 6

Poryphyria Cutanea Tarda

Answer 6

vesicles and bullae on sun-exposed areas

Question 7

IBD

Answer 7

pyoderma gangrenosum

Question 8

Crohn’s Disease

Answer 8

fissules in the inguinal folds

Question 9

GI Cancer/ leser trelat

Answer 9

sudden seborrheic keratosis

Question 10

Sarcoidosis

Answer 10

perioral/ facial papules/ on nose means lung sarcoidosis

Question 11

Diabetes

Answer 11

Acanthosis Nigricans: darkening of skin fold

Diabetic Dermopathy: brown macules and papules on the shins

Eruptive Xanthomas: mulberry yellow red papules

Diabetic Neuropathy:

Question 12

Hyperlipidemia

Answer 12

Tendinous Xanthoma

Plane Xanthoma

Xanthlasma Palpebrarum

Question 13

Sweet’s syndrome is present in

Answer 13

myelogenous leukemia and hemoorhagic disorders

Question 14

Oral lesions are present as

Answer 14

paraneoplastic pemphigous

Question 15

Paget’s disease of the breast

Answer 15

scaly red plaeuq -> breast cancer

Question 16

Relapsing polychondritis

Answer 16

swelling of the cartilage, and autoimmune rheumatic disorder

Question 17

Neurofibromatosis

Answer 17

cafe-au lait, areola, small soft skincoloed to pink polyploid neurofibromas

Question 18

Amyloidosis

Answer 18

keratototic, hyperpigmented plaques

Question 19

Calciphylaxis

Answer 19

esrd, necrotic skin