Cushings Disease Flashcards
0
Q
What causes the excess cortisol in Cushings?
A
Pituitary adenoma of the ACTH secreting cells
Adrenal tumour
Ectopic ACTH production
Iatrogenic (excess steroids)
1
Q
What is Cushings?
A
Excess cortisol due to a problem in the hypothalamic pituitary adrenal axis
2
Q
Signs and symptoms of Cushings
A
Central obesity and muscle wasting in limbs Thin skin with striae, easily bruised Hirsuitism - excess hair in women Poor wound healing Diabetes and hypertension Moon face and buffalo hump Osteoporosis Psychiatric illness Immune compromised
