Cushing Syndrome Flashcards
1
Q
10 SSx of Cushing Syndrome?
A
Moon facies Buffalo hump Purple striae Hypogonadism Disruption to menstrual cycle Central obesity Proximal myopathy Easy bruising Telangiectasia Acne Achilles tendon rupture
2
Q
What metabolic abnormality do you see in Cushing Syndrome?
A
Hypokalaemic metabolic alkalosis
3
Q
4 complications of Cushing Syndrome?
A
T2DM
Osteoporosis
Increased cardiovascular disease risk
Reduce immunity
4
Q
1st line investigation for Cushing’s syndrome?
A
Overnight dexamethasone suppression test/24 urinary cortisol
5
Q
How to differentiate between Cushing’s and Pseudo Cushing’s?
A
Insulin stress test
6
Q
Treatment of pituitary adenoma?
A
Chemical adrenalectomy i.e metyrapone
Transsphenoidal resection
7
Q
Treatment of adrenal adenoma/carcinoma?
A
Laparoscopic adrenalectomy
8
Q
Treatment of ectopic ACTH?
A
Treat underlying cause i.e lung cancer
Chemical adrenalectomy i.e metyrapone
