Acromegaly Flashcards
1
Q
What are 5 features of acromegaly?
A
Coarse facies Increased interdental spaces Protruding jaw (prognathism) Increased shoe size Weight gain Hypertension
2
Q
1st line test for acromegaly and why?
A
IGF-1. Highly sensitive so negative result can rule out acromegaly
3
Q
What type of cancer does acromegaly increase the risk of?
A
Colon cancer
4
Q
What is the 1st line Mx of acromegaly?
A
Transphenoidal surgery
5
Q
What are some complications of acromegaly?
A
Increased CVD risk Diabetes Hypertension Cardiomyopathy Obstructive sleep apnoea Carpal tunnel syndrome
6
Q
What is the diagnostic test for acromegaly?
A
OGTT: no GH suppression despite giving glucose