CT, MRI, and Nuclear Imaging Flashcards
Briefly describe what CT-scans are and how they work
- What it is → X-ray beam and detector within circular scanner that moves around the patient
- computer interprets (reconstructs) image
- tissues assigned different shades of gray
- series of cross-section slices (axial); can be reconstructed in sagittal and coronal planes, as well as 3D
Give several example indications for CT-scans (6)
- Bone and soft tissue tumors
- Fractures
- Intra-articular abnormalities
- Bone fragment detection
- Bone mineral analysis (i.e. metabolic disorders)
- Neuroimaging
limitation(s) of CT-scans
inability to distinguish small areas of different tissues
describe the scanning process in CT-scans
- Scout image (2D) taken to localize target structures
- Helical (spiraling) slices taken continuously with multiple-detector rows
- volumetric scanning possible with this, as structures can be made into 3D images
describe the data conversion process in CT-scans
- Radiodensities for each cubic millimeter
- Converted from digital signals into matrix
- each cell (pixel) assigned shade of gray
- Matrix transformed into an image
- Contrasts and window modification
list and describe 2 CT-scan variants
which one distinguishes osteophytes, ligaments, infolding, and disc material?
- 3D CT
- multiplantar reconstruction → images can be rotated in space on a computer screen
- CT Myelogram
- contrast material allows visualization of structures that impinge on neurologic structures
- distinguish osteophytes, ligaments infolding, and disc material
when viewing CT-scans, denser structures appear _________
more white
______is an advantage of CT-scans over radiograph
radiodensity free of superimposed tissues
what is voxel?
product of pixel and slice thickness
average density of different tissues represented from within the voxel
cross-sectional anatomy familiarity is important with CT-scans. List 3 different plane views and how to orient yourself with them
axial, sagittal, coronal
- Axial image → as if the pt were supine, viewing looking in caudocephalad direction
- Sagittal image → view form left to right
- Coronal image → view as if facing the pt
list CT-scan clinical applications pertaining to bone (7)
- subtle fracture
- degenerative changes
- serious trauma
- spinal stenosis
- IV disc pathology
- Intra-articular loose bodies
- Osseous alignment in any plane
list CT-scan clinical applications for neuroimaging (3)
- Acute trauma (initial assessments)
- SPECT
- PET
list benefits of CT-scans (compared to an MRI)
- less expensive than MR
- less time than MR and US
- benefits over problems related to physical barriers with MRI
list limitations with CT-scans
- given observation is based on radiodensity, tissues of similar radiodensity may not be distinguishable (e.g. tumors and surrounding soft tissues)
- radiation exposure
what is nuclear imaging?
imaging that uses radiopharmaceuticals (tracers) for the purpose of diagnosis, therapy, and research
can be used for static image or viewing over a period of time
what is the general indication for nuclear imaging?
testing function of tissues
diagnosis by physiological change (as opposed to structure)
describe the mechanism of nuclear imaging
- radionuclide (emits gamma rays) introduced
- absorbed differently by tissues based on metabolic activity
- gamma rays observed by special camera
- computer converts to digital image
list and briefly describe the 6 different methods of nuclear imaging
- Static → single image of targeted body region
- Whole-body → AP (example: bone scans)
- Dynamic → timed sequence
- SPECT → 3D
- PET → biologic function of cells
- Combinations with CT and MR
list indications for dynamic nuclear imaging
cardiac, hepatobiliary, gastric studies
what does SPECT stand for?
Single Photon Emission Computed Tomography
list indications for SPECT (4)
- bone
- cardiac perfusion
- brain
- liver
what does PET stand for?
Positron Emission Tomography
list indications for PET
CNS studies, tumors
list clinical indications for Nuclear Imaging
- Cancer
- staging, observation, and testing response to therapeutic intervention
- screening pts with a high risk for metastasis to bone
- Detection of metabolic bone diseases and other osteopathies
- Detection of other bone abnormality
list MSK indications for nuclear imaging
- HO
- fracture and stress fractures
- inflammation/infection
- complications of foreign hardware/prosthetic/medical device
- CRPS
- PFPS
- AVN
what is scintigraphy?
nuclear imaging of skeleton
what is the function of scintigraphy and how do you interpret it’s results?
function → confirm disease, ID extent of disease
black spots (aka hot spots) on image typically indicate increased uptake
what is a bone scan?
a nuclear imaging study of the skeleton comprised of 3 phases
list the 3 phases of a bone scan
- 1st phase → flow study (immediate)
- 2nd phase → blood pool (30 minutes)
- 3rd study → delayed (2-4 hours)
imaging occurs over the few hours post injection
list advantages/disadvantages of bone scans
- Advantages
- high sensitivity for changes in bone metabolism
- Disadvantages
- low specificity
- poor anatomic detail
list contraindications for bone scans
pregnancy
currently breast-feeding
list indications for MRI (3)
- soft tissue trauma
- internal joint derangement
- tumors
list 2 variants of MRI scanners
open scanners
upright scanners
give a brief explanation of how MRIs work
- MRIs measure the energy emitted by hydrogen nuclei as the respond to radiofrequency signals
- energy differs by tissue
- a radiofrequency wave pulse is applied at a right angle to align protons (hydrogen) in transverse plane which brings them to a higher energy state
- as the protons realign with the magnetic field they release absorbed energy which creates a current that is induced in receiver coil
- a contrast in image produced by different T1, T2 and # of hydrogen nuclei
what does T1 and T2 mean?
technical terms that refer to the time taken between magnetic pulses and the image is taken
describe T1 MRI
weighted images that measure energy from structures that give up energy quickly (like fat)
good for anatomic detail
tissues with higher water content appear darker
describe T2 MRI
weighted images that measure energy from structures that give up energy slowly (like water)
fat appears darker
grainer, less spatial resolution
good for ID of inflammation
list several clinical applications for MRI (5)
- sensitive to changes in bone marrow → dx of bone tumor, stress frxs, AVN
- Soft tissue injuries
- ligament and tendon
- meniscus
- alternative to arthroscopic dx
- disc pathology/neurologic impingement
- Tumor staging
- MR arthrography → arthrogram + MRI
- MR Myelography → view spinal canal and subarachnoid space w/high resolution MRI + strong T2 weighing
list limitations to MRI
- imaging for bone
- time for image
- high cost/expensive
- hardware can cause distortion of images
- physical limitations with procedure parameters
- ability to stay still
- claustrophobic
list contraindications to MRI
ferromagnetic metals (surgical clips, shrapnel)