CSIM1.67 68 Protozoan & helminth Parasitic D/z Flashcards
Giardia - route of transmission, life cycle, clinical features
2 nuclei, flaggella, microscopic parasite.
Faecal oral, contaminated water,
Giardia is contracted by ingesting its cysts. They go to small intestine and become trophozoites which are released. Trophozoites cause damage to gut mucosa, cause diarrhea and malabsorption. Trophozoites form cysts and are released in faeces.
Clinal ft - watery diarrhea, mild abdo pain, bloating, fatigue and gas build up.
Symptoms of cryptosporidia, microspora and isosporal belli
Similar to giardia, diarrhea, abdominal pain.
Entamoeba histolytica - transmission, life cycle, clinical features
Faecal oral, cysts in faecea.
Once ingested, go to gut and release trophozoites.
Clinical ft - most asymptomatic, some invade mucosa cause ulceration and bloody diarrhea and amoebic dysentery.
If invade blood stream, go to liver and cause amoebic liver abscess
Consequences of an amoebic liver abscess
Fever, Jaundice, anaemia and pain right flank
What is myasis?
Myasis is the parasitic infestation of fly-larvae in a mammal (human), while feeding on its tissue.
How does a tumbu fly myasis come about?
Tumbu fly lays eggs in soil, after eggs hatch, larvae come out and find a host.
If they find a host, they penetrate the skin and start developing inside.
Once mature, it unburrows and drops out of the human skin where it continues its life cycle.
How to treat tumbu fly myasis
Cover the entry wound with vaseline to suffocate the larvae
Larvae will crawl out and then use tweezer to extract.
How to prevent tumbu fly myasis?
Iron your clothes!
What organism transmist trypanosomiasis?
Tsetse fly
What is trypanosmiasis also known as?
Sleeping sickness
What is the life cycle of trypanosomiasis?
Saliva of tsetse fly, bites human and lives in various fluid compartment of the human
Multiple within the body and be ready for when the next tsetse fly bites the human
Symptoms of trypanosomiasis?
Primary chancre, local lymphadenopathy, fever, headache, cutaenous edema, itching, myocarditis, jaundice, anaemia, effusions, chronic meningoencephalitis.
Sleep disturbance - sleep day time, restless night time.
What carries leishmaniasis?
Female sandflies.
What species cause visceral leishmaniasis and cutaneous leishmaniasis?
Visceral - L donovani and L aethiopica
Cutaenous - most other species other than the above.
Cause and clinical features of visceral leishmaniasis?
Caused by lymphatic spread of parasite around body
Systemic effects - episodic fevers, rigors, swears, weight loss, malaise, anorexia and hepatosplenomegaly
Skin effects - hyperpigmentation on the face, hands, feet and abdomen
Clinical features of cutaneous leishmaniasis?
Lesion forming around bite, becomes itchy papule which falls off to become an ulcer.
What is ancylostoma duodenale?
AKA hookworm