CSF SQ Flashcards
The functions of the CSF include all of the following
except:
A. Removing metabolic wastes
B. Producing an ultrafiltrate of plasma
C. Supplying nutrients to the CNS
D. Protecting the brain and spinal cord
B. Producing an ultrafiltrate of plasma
The CSF flows through the:
A. Choroid plexus
B. Pia mater
C. Arachnoid space
D. Dura mater
C. Arachnoid space
Substances present in the CSF are controlled by the:
A. Arachnoid granulations
B. Blood–brain barrier
C. Presence of one-way valves
D. Blood–CSF barrier
B. Blood–brain barrier
What department is the CSF tube labeled 3 routinely
sent to?
A. Hematology
B. Chemistry
C. Microbiology
D. Serology
A. Hematology
The CSF tube that should be kept at room temperature is:
A. Tube 1
B. Tube 2
C. Tube 3
D. Tube 4
B. Tube 2
Place the appropriate letter in front of the statement that best describes CSF specimens in these two conditions:
A. Traumatic tap
B. Intracranial hemorrhage
____ Even distribution of blood in all tubes
____ Xanthochromic supernatant
____ Concentration of blood in tube 1 is greater than in tube 3
____ Specimen contains clots
B
B
A
A
The presence of xanthochromia can be caused by all of the following except:
A. Immature liver function
B. RBC degradation
C. A recent hemorrhage
D. Elevated CSF protein
C. A recent hemorrhage
A web-like pellicle in a refrigerated CSF specimen indicates:
A. Tubercular meningitis
B. Multiple sclerosis
C. Primary CNS malignancy
D. Viral meningitis
A. Tubercular meningitis
unit: cells counted, 80; dilution, 1:10; large Neubauer squares counted, 10.
A. 8
B. 80
C. 800
D. 8000
C. 800
A CSF WBC count is diluted with:
A. Distilled water
B. Normal saline
C. Acetic acid
D. Hypotonic saline
C. Acetic acid
A total CSF cell count on a clear fluid should be:
A. Reported as normal
B. Not reported
C. Diluted with normal saline
D. Counted undiluted
D. Counted undiluted
The purpose of adding albumin to CSF before cytocentrifugation is to:
A. Increase the cell yield
B. Decrease the cellular distortion
C. Improve the cellular staining
D. Both A and B
D. Both A and B
The primary concern when pleocytosis of neutrophils and
lymphocytes is found in the CSF is:
A. Meningitis
B. CNS malignancy
C. Multiple sclerosis
D. Hemorrhage
A. Meningitis
Neutrophils with pyknotic nuclei may be mistaken for:
A. Lymphocytes
B. Nucleated RBCs
C. Malignant cells
D. Spindle-shaped cells
B. Nucleated RBCs
The presence of which of the following cells is increased
in a parasitic infection?
A. Neutrophils
B. Macrophages
C. Eosinophils
D. Lymphocytes
C. Eosinophils
Macrophages appear in the CSF after:
A. Hemorrhage
B. Repeated spinal taps
C. Diagnostic procedures
D. All of the above
D. All of the above
Nucleated RBCs are seen in the CSF as a result of:
A. Elevated blood RBCs
B. Treatment of anemia
C. Severe hemorrhage
D. Bone marrow contamination
D. Bone marrow contamination
After a CNS diagnostic procedure, which of the following
might be seen in the CSF?
A. Choroidal cells
B. Ependymal cells
C. Spindle-shaped cells
D. All of the above
D. All of the above
Hemosiderin granules and hematoidin crystals are seen in:
A. Lymphocytes
B. Macrophages
C. Ependymal cells
D. Neutrophils
B. Macrophages
Myeloblasts are seen in the CSF:
A. In bacterial infections
B. In conjunction with CNS malignancy
C. After cerebral hemorrhage
D. As a complication of acute leukemia
D. As a complication of acute leukemia
Cells resembling large and small lymphocytes with
cleaved nuclei represent:
A. Lymphoma cells
B. Choroid cells
C. Melanoma cells
D. Medulloblastoma cells
A. Lymphoma cells
The reference range for CSF protein is:
A. 6 to 8 g/dL
B. 15 to 45 g/dL
C. 6 to 8 mg/dL
D. 15 to 45 mg/dL
D. 15 to 45 mg/dL
CSF can be differentiated from serum by the presence of:
A. Albumin
B. Globulin
C. Prealbumin
D. Tau transferrin
B. Globulin
In serum, the second most prevalent protein is IgG; in
CSF, the second most prevalent protein is:
A. Transferrin
B. Prealbumin
C. IgA
D. Ceruloplasmin
B. Prealbumin
Elevated CSF protein values can be caused by all of the
following except:
A. Meningitis
B. Multiple sclerosis
C. Fluid leakage
D. CNS malignancy
C. Fluid leakage
The integrity of the blood–brain barrier is measured using
the:
A. CSF/serum albumin index
B. CSF/serum globulin ratio
C. CSF albumin index
D. CSF IgG index
A. CSF/serum albumin index
Given the following results, calculate the IgG index: CSF IgG,
50 mg/dL; serum IgG, 2 g/dL; CSF albumin, 70 mg/dL;
serum albumin, 5 g/dL.
A. 0.6
B. 6.0
C. 1.8
D. 2.8
C. 1.8
The CSF IgG index calculated in Study Question 27
indicates:
A. Synthesis of IgG in the CNS
B. Damage to the blood–brain barrier
C. Cerebral hemorrhage
D. Lymphoma infiltration
A. Synthesis of IgG in the CNS
The finding of oligoclonal bands in the CSF and not in the serum is seen with:
A. Multiple myeloma
B. CNS malignancy
C. Multiple sclerosis
D. Viral infections
C. Multiple sclerosis
A CSF glucose of 15 mg/dL, WBC count of 5000, 90% neutrophils, and protein of 80 mg/dL suggests:
A. Fungal meningitis
B. Viral meningitis
C. Tubercular meningitis
D. Bacterial meningitis
D. Bacterial meningitis
A patient with a blood glucose of 120 mg/dL would have a normal CSF glucose of:
A. 20 mg/dL
B. 60 mg/dL
C. 80 mg/dL
D. 120 mg/dL
B. 60 mg/dL
CSF lactate will be more consistently decreased in:
A. Bacterial meningitis
B. Viral meningitis
C. Fungal meningitis
D. Tubercular meningitis
A. Bacterial meningitis
Measurement of which of the following can be replaced by
CSF glutamine analysis in children with Reye syndrome?
A. Ammonia
B. Lactate
C. Glucose
D. α -Ketoglutarate
A. Ammonia
Before performing a Gram stain on CSF, the specimen must be:
A. Filtered
B. Warmed to 37°C
C. Centrifuged
D. Mixed
C. Centrifuged
All of the following statements are true about cryptococcal
meningitis except:
A. An India ink preparation is positive
B. A starburst pattern is seen on Gram stain
C. The WBC count is over 2000
D. A confirmatory immunology test is available
C. The WBC count is over 2000
The test of choice to detect neurosyphilis is the:
A. RPR
B. VDRL
C. FAB
D. FTA-ABS
D. FTA-ABS
