Amniotic Fluid Flashcards
Which of the following is not a function of amniotic fluid?
A. Allows movement of the fetus
B. Allows carbon dioxide and oxygen exchange
C. Protects fetus from extreme temperature changes
D. Acts as a protective cushion for the fetus
B. Allows carbon dioxide and oxygen exchange
What is the primary cause of the normal increase in amniotic fluid as a pregnancy progresses?
A. Fetal cell metabolism
B. Fetal swallowing
C. Fetal urine
D. Transfer of water across the placenta
C. Fetal urine
Which of the following is not a reason for decreased
amounts of amniotic fluid?
A. Fetal failure to begin swallowing
B. Increased fetal swallowing
C. Membrane leakage
D. Urinary tract defects
A. Fetal failure to begin swallowing
Why might a creatinine level be requested on an amniotic
fluid?
A. Detect oligohydramnios
B. Detect polyhydramnios
C. Differentiate amniotic fluid from maternal urine
D. Evaluate lung maturity
C. Differentiate amniotic fluid from maternal urine
Amniotic fluid specimens are placed in amber-colored tubes prior to sending them to the laboratory to prevent the
destruction of:
A. Alpha-fetoprotein
B. Bilirubin
C. Cells for cytogenetics
D. Lecithin
B. Bilirubin
How are specimens for FLM testing delivered to and stored in the laboratory?
A. Delivered on ice and refrigerated
B. Immediately centrifuged
C. Kept at room temperature
D. Delivered in a vacuum tube
A. Delivered on ice and refrigerated
Why are amniotic specimens for cytogenetic analysis incubated at 37°C prior to analysis?
A. To detect the presence of meconium
B. To differentiate amniotic fluid from urine
C. To prevent photo-oxidation of bilirubin to biliverdin
D. To prolong fetal cell viability and integrity
D. To prolong fetal cell viability and integrity
- Match the following colors in amniotic fluid with their
significance.
___ A. Colorless 1. Fetal death
___ B. Dark green 2. Normal
___ C. Red-brown 3. Presence of bilirubin
___ D. Yellow 4. Presence of meconium
2
4
1
3
A significant rise in the OD of amniotic fluid at 450 nm indicates the presence of which analyte?
A. Bilirubin
B. Lecithin
C. Oxyhemoglobin
D. Sphingomyelin
A. Bilirubin
Plotting the amniotic fluid OD on a Liley graph represents
the severity of hemolytic disease of the newborn. A value
that is plotted in zone II indicates what condition of the
fetus?
A. No hemolysis
B. Mildly affected fetus
C. Moderately affected fetus that requires close monitoring
D. Severely affected fetus that requires intervention
C. Moderately affected fetus that requires close monitoring
The presence of a fetal neural tube disorder may be
detected by:
A. Increased amniotic fluid bilirubin
B. Increased maternal serum alpha-fetoprotein
C. Decreased amniotic fluid phosphatidyl glycerol
D. Decreased maternal serum acetylcholinesterase
B. Increased maternal serum alpha-fetoprotein
True or False: An AFP MoM value greater than two times
the median value is considered an indication of a neural
tube disorder.
True
When severe HDN is present, which of the following tests
on the amniotic fluid would the physician not order to
determine whether the fetal lungs are mature enough to
withstand a premature delivery?
A. AFP levels
B. Foam stability index
C. Lecithin/sphingomyelin ratio
D. Phosphatidyl glycerol detection
A. AFP levels
True or False: Prior to 35 weeks’ gestation, the normal L/S
ratio is less than 1.6.
True
When performing an L/S ratio by thin-layer chromatography,
a mature fetal lung will show:
A. Sphingomyelin twice as concentrated as lecithin
B. No sphingomyelin
C. Lecithin twice as concentrated as sphingomyelin
D. Equal concentrations of lecithin and sphingomyelin
C. Lecithin twice as concentrated as sphingomyelin
