CSF pathologies Flashcards
Where is CSF produced and absorbed from?
Produced from the choroid plexus
Absorbed from the arachnoid granulations
List some examples of CSF pathologies
Hydrocephalus
Normal pressure hydrocephalus
Idiopathic intracranial hypertension
Spontaneous intracranial hypotension
Syringomyelia
Cerebral oedema
What are some of the clinical signs and features of hydrocephalus from birth?
Large head
Thin and shiny skin on the scalp with visible veins
Bulging fontanelle
“sunsetting”
Poor feeding
Irritability
Shunts can be used in the management of hydrocephalus. Possible complications include blockage and infection. What are some of the signs of blockage?
Headache and vomiting
Sunsetting in children, lack of upgaze in adults
Blurred vision (papilloedema)
What are the triad of symptoms which occur with normal pressure hydrocephalus?
Urinary incontinence, ataxia and memory loss
Who gets idiopathic intracranial hypertension
Young, overweight females
What conditions are associated with idiopathic intracranial hypertension?
Sleep apnoea
Hypothyroidism
Addison’s
SLE
What drugs are associated with idiopathic intracranial hypertension
Lithium
Steroid withdrawal
Antibiotics
Combined oral contraceptive pill
What are some of the signs and symptoms of idiopathic intracranial hypertension?
Horrific headaches
Papilloedema
What is the best form of management for idiopathic intracranial hypertension?
WEIGHT LOSS
Diuretics and shunts can also be considered
What is spontaneous intracranial hypotension and what are some of the possible symptoms?
rare cause of headaches that results from a CSF leak
Orthostatic headaches
Neck/ interscapular/ arm pain
Diplopia
Muffled hearing
Impaired sphincter control
Galactorrhoea
What are some of the causes of spontaneous intracranial hypotension?
Idiopathic
Collagen disorders e.g Marfan’s
Trauma
What is syringomyelia?
Cystic enlargement of the spinal cord causing central cord compression
Which spinal cord tracts are affected by syringomyelia?
Spinothalamic tract
(loss of pain, pressure, temperature and crude touch)
Corticospinal
(muscle atrophy, weakness and paralysis)
What is the most common cause of syringomyelia?
Arnold Chiari II malformation