CSF Chemistry

Question 1

Plasma glucose value

Answer 1

60-70%

Question 2

Plasma glucose [Difference]

Answer 2

100 mg/dl

Question 3

CSF glucose [difference]

Answer 3

65 mg/dl

Question 4

Blood glucose should be drawn______ prior to lumbar tap

Answer 4

2 hours

Question 5

Can be used to determine the cause of

Answer 5

meningitis

Question 6

Always a result of plasma elevations

Answer 6

↑ Level of csf glucose

Question 7

Caused by alteration in transport in BBB and increased used by brain cells

Answer 7

Decrease Level of csf glucose

Question 8

Destruction of tissue within the CNS due to____ causes the production of ↑ CSF Lactate

Answer 8

hypoxia

Question 9

CSF Lactate aids in the _____ and _____ of meningitis

Answer 9

diagnosis
management

Question 10

CSF lactate used to monitor_____

Answer 10

severe head injuries

Question 11

CSF lactate increase level in

Answer 11

Bacterial, tubercular, fungal meningitis

Question 12

CSF lactate decreases level rapidly

Answer 12

When treatment is successful

Question 13

[CSF Lactate] falsely elevated

Answer 13

Xanthochromic
Hemolyzed specimens

Question 14

Indirect measurement of CSF Ammonia

Answer 14

CSF glutamine

Question 15

Ammonia is _____ (evaporates easily)

Answer 15

Volatile

Question 16

Glutamine produced from _____ and _____by the brain cells

Answer 16

Ammonia & α-ketoglutarate

Question 17

Toxic to CNS tissues

Answer 17

Ammonia

Question 18

Indirect test for the presence of excess ammonia in CSF

Answer 18

Glutamine

Question 19

[CSF Glutamine] normal values

Answer 19

8-18 mg/dl

Question 20

Increase level [CSF Glutamine]

Answer 20

Liver disorder (increased blood and CSF ammonia)
Children with Reye’s Syndrome

Question 21

Frequently requested procedure for patients with

Answer 21

coma of unknown origin