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Aubf Book Based TOMO EXAM > CSF > Flashcards

CSF Flashcards

1
Q
  1. CSF is produced mainly in the:
    A. Bone marrow
    B. Peripheral blood
    C. Choroid plexuses
    D. Subarachnoid space
A

C. Choroid plexuses

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2
Q
  1. The functions of the CSF include all of the following except:
    A. Removing metabolic wastes
    B. Producing an ultrafiltrate of plasma
    C. Supplying nutrients to the CNS
    D. Protecting the brain and spinal cord
A

B. Producing an ultrafiltrate of plasma

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3
Q
  1. The CSF flows through the:
    A. Choroid plexus
    B. Pia mater
    C. Subarachnoid space
    D. Dura mater
A

C. Subarachnoid space

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4
Q
  1. Substances present in the CS are controlled by the:
    A. Arachnoid granulations
    B. Blood-brain barrier
    C. Presence of one-way valves
    D. Blood-CSF barrier
A

B. Blood-brain barrier

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5
Q
  1. What department is the CSF tube labeled 3 routinely sent to?
    A. Hematology
    B. Chemistry
    C. Microbiology
    D. Serology
A

A. Hematology

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6
Q
  1. The CS tube that should be kept at room temperature is:
    A. Tube 1
    B. Tube 2
    C. Tube 3
    D. Tube 4
A

B. Tube 2

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7
Q
  1. The presence of xanthochromia can be B. Tube 2 caused by all of the following except:
    A. Immature liver function
    B. RBC degradation
    C. A recent hemorrhage
    D. Elevated CSF protein
A

C. A recent hemorrhage

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8
Q
  1. A web-like pellicle in a refrigerated CSF specimen indicates:
    A. Tubercular meningitis
    B. Multiple sclerosis
    C. Primary CNS malignancy
    D. Viral meningitis
A

A. Tubercular meningitis

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9
Q
  1. Given the following information, calculate the CSF WBC count: cells counted, 80; dilution, 1:10; large Neubauer squares counted, 10.
    A. 8
    B. 80
    C. 800
    D. 8000
A

C. 800

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10
Q
  1. A CSF WBC count is diluted with:
    A. Distilled water
    B. Normal saline
    C. Acetic acid
    D. Hypotonic saline
A

C. Acetic acid

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11
Q
  1. A total CSF cell count on a clear fluid should be:
    A. Reported as normal
    B. Not reported
    C. Diluted with normal saline
    D. Counted undiluted
A

D. Counted undiluted

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12
Q
  1. The purpose of adding albumin to CSF before cytocentrifugation is to:
    A. Increase the cell yield
    B. Decrease the cellular distortion
    C. Improve the cellular staining
    D. Both A and B
A

D. Both A. Increase the cell yield and B. Decrease the cellular distortion

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13
Q
  1. The primary concern when pleocytosis of neutrophils and lymphocytes is found in the CSF is:
    A. Meningitis
    B. CNS malignancy
    C. Multiple sclerosis
    D. Hemorrhage
A

A. Meningitis

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14
Q
  1. Neutrophils with pyknotic nuclei may be mistaken for:
    A. Lymphocytes
    B. Nucleated RBCs
    C. Malignant cells
    D. Spindle-shaped cells
A

B. Nucleated RBCs

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15
Q
  1. The presence of which of the following cells is increased in a parasitic infection?
    A. Neutrophils
    B. Macrophages
    C. Eosinophils
    D. Lymphocytes
A

C. Eosinophils

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16
Q
  1. Macrophages appear in the CSF after:
    A. Hemorrhage
    B. Repeated spinal taps
    C. Diagnostic procedures
    D. All of the above
A

D. All of the above

17
Q
  1. Nucleated RBCs are seen in the CSF as a result of:
    A. Elevated blood RBCs
    B. Treatment of anemia
    C. Severe hemorrhage
    D. Bone marrow contamination
A

D. Bone marrow contamination

18
Q
  1. After a CNS diagnostic procedure, which of the following might be seen in the CSF?
    A. Choroidal cells
    B. Ependymal cells
    C. Spindle-shaped cells
    D. All of the above
A

D. All of the above

19
Q
  1. Hemosiderin granules and hematoidin crystals are seen in:
    A. Lymphocytes
    B. Macrophages
    C. Ependymal cells
    D. Neutrophils
A

B. Macrophages

20
Q
  1. Myeloblasts are seen in the CSF:
    A. In bacterial infections
    B. In conjunction with CNS malignancy
    C. After cerebral hemorrhage
    D. As a complication of acute leukemia
A

D. As a complication of acute leukemia

21
Q
  1. Cells resembling large and small lymphocytes with cleaved nuclei represent:
    A. Lymphoma cells
    B. Choroid cells
    C. Melanoma cells
    D. Medulloblastoma cells
A

A. Lymphoma cells

22
Q
  1. The reference range for CS protein is:
    A. 6 to 8 g/dL
    B. 15 to 45 g/dL
    C. 6 to 8 mg/dL
    D. 15 to 45 mg/dL
A

B. 15 to 45 g/dL

23
Q
  1. CS can be differentiated from serum by the presence of:
    A. Albumin
    B. Globulin
    C. Transthyretin
    D. Tau transferrin
A

D. Tau transferrin

24
Q
  1. In serum, the second most prevalent protein is IgG; in CS, the second most prevalent protein is:
    A. Transferrin
    B. Transthyretin
    C. Prealbumin
    D. Ceruloplasmin
A

C. Prealbumin

25
Q
  1. Elevated values for CSF protein can be caused by all of the following except:
    A. Meningitis
    B. Multiple sclerosis
    C. Fluid leakage
    D. CNS malignancy
A

C. Fluid leakage

26
Q
  1. The integrity of the blood-brain barrier is measured using the:
    A. CSF/serum albumin index
    B. CSF/serum globulin ratio
    C. CSF albumin index
    D. CSF IgG index
A

A. CSF/serum albumin index

27
Q
  1. Given the following results, calculate the IgG index: CSF IgG, 50 mg/dL; serum IgG, 2 g/dL; CSF albumin, 70 mg/dL; serum albumin, 5 g/dL.
    A. 0.6
    B. 6.0
    C. 1.8
    D. 2.8
A

C. 1.8

28
Q
  1. The CSF IgG index calculated in Study Question 28 indicates:
    A. Synthesis to IgG in the CNS
    B. Damage to the blood-brain barrier
    C. Cerebral hemorrhage
    D. Lymphoma infiltration
A

A. Synthesis to IgG in the CNS

29
Q
  1. The finding of oligoclonal bands in the CSF and not in the serum is seen with:
    A. Multiple myeloma
    B. CNS malignancy
    C. Multiple sclerosis
    D. Viral infections
A

C. Multiple sclerosis

30
Q
  1. Which condition is suggested by the following results: a CSF glucose of 15 mg/dL, WBC count of 5000, 90% neutrophils, and protein of 80 mg/dL?
    A. Fungal meningitis
    B. Viral meningitis
    C. Tubercular meningitis
    D. Bacterial meningitis
A

D. Bacterial meningitis

31
Q
  1. A patient with a blood glucose of 120 mg/dL. would have a normal CSF glucose of:
    A. 20 mg/dL
    B. 60 mg/di.
    C. 80 mg/di.
    D. 120 mg/dL
A

C. 80 mg/di.

32
Q
  1. CS lactate will be more consistently decreased in:
    A. Bacterial meningitis
    B. Viral meningitis
    C. Fungal meningitis
    D. Tubercular meningitis
A

B. Viral meningitis

33
Q
  1. Measurement of which of the following can be replaced by CSF glutamine analysis in children with Reye syndrome?
    A. Ammonia
    B. Lactate
    C. Glucose
    D. a-Ketoglutarate
A

A. Ammonia

34
Q
  1. Before performing a Gram stain on CSF, the specimen must be:
    A. Filtered
    B. Warmed to 37°C
    C. Centrifuged
    D. Mixed
A

C. Centrifuged

35
Q
  1. All of the following statements are true about cryptococcal meningitis except:
    A. An India ink preparation is positive
    B. A starburst pattern is seen on Gram stain
    C. The WBC count is over 2000
    D. A confirmatory immunology test is available
A

C. The WBC count is over 2000

36
Q
  1. The most sensitive and specific method to detect the causative organism in meningitis is:
    A. Gram stain
    B. Culture and sensitivity
    C. India ink stain
    D. PCR assay
A

D. PCR assay

37
Q
  1. The test of choice to detect neurosyphilis is the:
    A. RPR
    B. VDRL
    C. FAB
    D. FIA-ABS
A

B. VDRL

Aubf Book Based TOMO EXAM (5 decks)

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