cryoglobulinemias Flashcards
1
Q
What are the three types of cryoglobulinemias and their causes?
A
Type 1: monoclonal IgM>IgG
Type 2: monoclonal IgM or IgG with polyclonal IgG
Type 3: Polyclonal IgM with polyclonal IgG
2
Q
How does type 1 cryoglobulinemia present?
A
lived reticular, raynauds, acrocyanosis, purpura, and ulcerations
3
Q
The majority of types 2 and 3 cryoglobulinemias are a/w:
A
Hepatitis C (80-90%)
4
Q
Type I cryoglobulinemia is a/w:
A
lymphoproliferative disorders (multiple myeloma)
5
Q
Labs to check for cryoglobulinemias:
A
cryoglobulins increased
- decreased C4 complement
- RF
- Hepatitis panel
