Cross-modular enzymes Flashcards

1
Q

Defects in what enzyme cause Alkaptonuria?

A

homogentisate 1,2-dioxygenase (HGD)

Converts homogentisic acid –> methylacetoacetic acid

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2
Q

Defects in what enzyme cause Phenylketonuria (PKU)?

A

Phenylalanine hydroxylase

Converts phenylalanine –> tyrosine

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3
Q

Defects in what enzyme cause Oculocutaneous albinism?

A

Tyrosinae

Converts hydroxyphenylpyruvic acid –> DOPA

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