Crohn's vs. Ulcerative colitis Flashcards
Terminal ileum
hallmark location of Crohn’s
Involves the rectum in all cases
Ulcerative colitis
Transmural involvement
Crohn’s
Involves only mucosa and submucosa
Ulcerative colitis
Can involve anywhere from anus to mouth
Crohn’s
Confined to rectum and colon
Ulcerative colitis
Fistulae and abscesses
Crohn’s
Sclerosing cholangitis and colorectal cancer
Ulcerative colitis
Toxic megacolon
Ulcerative colitis
Bloody diarrhea
Ulcerative colitis
Skip lesions - discontinuous involvement
Crohn’s
No skip lesions - continuous involvement
Ulcerative colitis
No cure, and recurrence is common even after surgery
Crohn’s
Surgical treatment (total colectomy) is often curative
Ulcerative colitis
Sulfasalazine (5-ASA) is used for both but is more effective in:
Ulcerative colitis